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Tmem5 Gene Detail
Summary
  • Symbol
    Tmem5
  • Name
    transmembrane protein 5
  • Synonyms
    6330415D21Rik, MGC:28135
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384919
    NCBI Gene: 216395
Location & Maps
more
  • Sequence Map
    Chr10:122078114-122097371 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19258 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 70.25 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM5, transmembrane protein 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM5, transmembrane protein 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HP10481, MDDGA10
  • Links
    NCBI Gene ID: 10329
    neXtProt AC: NX_Q9Y2B1

  • Chr Location
    12q14.2; chr12:63779803-63809558 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8600
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TMEM5
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human TMEM5 associations

Human Disease Mouse Models
       Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 10; MDDGA10   OMIM: 615041
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027721 VEGA Gene Model | MGI Sequence Detail 19258 C57BL/6J ±  kb
transcript OTTMUST00000068598 VEGA | MGI Sequence Detail 4793 Not Applicable  
polypeptide OTTMUSP00000034721 VEGA | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    207 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032631 transmembrane protein 5
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913925
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory