About   Help   FAQ
Hkdc1
Gene Detail
Symbol

Name
ID
Hkdc1
hexokinase domain containing 1
MGI:2384910
Synonyms
MGC:28816
Feature Type
protein coding gene
Genetic Map
Chromosome 10
32.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:62383137-62422491 bp, - strand
From VEGA annotation of GRCm38

  39355 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128937  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HKDC1
Protein SuperFamily: hexokinase I
Gene Tree: Hkdc1

Human
homologs
HKDC1, hexokinase domain containing 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 80201
neXtProt AC: NX_Q2TB90

Human Chr (Location): 10q22.1; chr10:69220303-69267559 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hkdc1 interacts with 81 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process carbohydrate metabolic process, carbohydrate phosphorylation, ...
Component cytosol
Function ATP binding, fructokinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (376)    Tissues (121)    Images (79)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 376
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hk2 ; ZFIN hkdc1    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000024651 (Evidence)
Ensembl Gene Model ENSMUSG00000020080 (Evidence)
Entrez Gene 216019 (Evidence)
UniGene 213213
DFCI TC1587311, TC1612518
DoTS DT.94215497, DT.97345227
NIA Mouse Gene Index U031847
EC 2.7.1.1
Consensus CDS Project CCDS23888.1
International Mouse Phenotyping Consortium Status Hkdc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024651 VEGA Gene Model | MGI Sequence Detail 39355 C57BL/6J ±  kb
transcript OTTMUST00000060622 VEGA | MGI Sequence Detail 3517 Not Applicable 
polypeptide OTTMUSP00000029588 VEGA | MGI Sequence Detail 915 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(8) UniProt(1)
Polymorphisms
SNPs within 2kb(214 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001312 Hexokinase
InterPro IPR019807 Hexokinase, conserved site
InterPro IPR022673 Hexokinase, C-terminal
InterPro IPR022672 Hexokinase, N-terminal
Protein Ontology PR:000029546 hexokinase HKDC1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory