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Slc24a1 Gene Detail
Summary
  • Symbol
    Slc24a1
  • Name
    solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
  • Synonyms
    MGC:27617
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384871
    NCBI Gene: 214111
Location & Maps
more
  • Sequence Map
    Chr9:64922861-64951607 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28747 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC24A1, solute carrier family 24 member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC24A1, solute carrier family 24 member 1
    Orthology source: HomoloGene
  • Synonyms
    CSNB1D, HsT17412, NCKX, NCKX1, RODX
  • Links
    NCBI Gene ID: 9187
    neXtProt AC: NX_O60721

  • Chr Location
    15q22; chr15:65611405-65661242 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SLC24A1 associations

Human Disease Mouse Models
       Night Blindness, Congenital Stationary, Type 1D; CSNB1D   OMIM: 613830
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Genomic Mutations
    1 involving Slc24a1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 214111 NCBI Gene Model | MGI Sequence Detail 28747 C57BL/6J ±  kb
transcript NM_144813 RefSeq | MGI Sequence Detail 5244 Not Specified  
polypeptide NP_659062 RefSeq | MGI Sequence Detail 1130 Not Specified  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    219 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR004837 Sodium/calcium exchanger membrane region
    IPR004481 Sodium/potassium/calcium exchanger
    IPR004817 Sodium/potassium/calcium exchanger 1
Molecular
Reagents
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  • All nucleic 27
    cDNA 26
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory