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Ap1ar Gene Detail
Summary
  • Symbol
    Ap1ar
  • Name
    adaptor-related protein complex 1 associated regulatory protein
  • Synonyms
    Gadkin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384822
    NCBI Gene: 211556
  • Gene Overview
    MyGene.info: AP1AR
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:127807007-127837518 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 56.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    393 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384822
protein coding gene Chr3:127807007-127837523 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027866
protein coding gene Chr3:130318415-130350787 (-)
A/J MGP_AJ_G0027824
protein coding gene Chr3:125851799-125882426 (-)
AKR/J MGP_AKRJ_G0027789
protein coding gene Chr3:129106001-129138065 (-)
BALB/cJ MGP_BALBcJ_G0027837
protein coding gene Chr3:125713195-125743439 (-)
C3H/HeJ MGP_C3HHeJ_G0027566
protein coding gene Chr3:129480835-129515217 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028281
protein coding gene Chr3:135017721-135049223 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025619
protein coding gene Chr3:121096989-121126768 (-)
CAST/EiJ MGP_CASTEiJ_G0027023
protein coding gene Chr3:129054124-129083891 (-)
CBA/J MGP_CBAJ_G0027542
protein coding gene Chr3:139582699-139618153 (-)
DBA/2J MGP_DBA2J_G0027683
protein coding gene Chr3:125068919-125098672 (-)
FVB/NJ MGP_FVBNJ_G0027650
protein coding gene Chr3:122655254-122685110 (-)
LP/J MGP_LPJ_G0027792
protein coding gene Chr3:131865384-131901132 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027681
protein coding gene Chr3:147530591-147561563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028338
protein coding gene Chr3:128747539-128786787 (-)
PWK/PhJ MGP_PWKPhJ_G0026747
protein coding gene Chr3:124804402-124833987 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026572
protein coding gene Chr3:126825995-126855674 (-)
WSB/EiJ MGP_WSBEiJ_G0027102
protein coding gene Chr3:129473807-129504904 (-)



Homology
more
  • Human Ortholog
    AP1AR, adaptor related protein complex 1 associated regulatory protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AP1AR, adaptor related protein complex 1 associated regulatory protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2C18, C4orf16, gamma-BAR, GBAR, PRO0971
  • Links
    NCBI Gene ID: 55435
    neXtProt AC: NX_Q63HQ0
    UniProt: Q63HQ0

  • Chr Location
    4q25; chr4:112231727-112273110 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10236
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AP1AR
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Ap1ar
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211556 NCBI Gene Model | MGI Sequence Detail 30512 C57BL/6J ±  kb
transcript NM_145964 RefSeq | MGI Sequence Detail 2679 C57BL/6  
polypeptide NP_666076 RefSeq | MGI Sequence Detail 298 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR031483 AP-1 complex-associated regulatory protein
Molecular
Reagents
less
  • All nucleic 65
    cDNA 65

    Microarray probesets 6
Other
Accession IDs
less
MGI:2139553, MGI:2140060
References
more
  • Summaries
    All 35
    Diseases 1
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:250938 Mertins P, et al., An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling. Cell Rep. 2017 Jun 27;19(13):2853-2866

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory