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Ap1ar
Gene Detail
 Symbol
Name
ID
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
MGI:2384822
Synonyms Gadkin
Feature Type protein coding gene
Genetic Map
Chromosome 3
56.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:127807264-127837492 bp, - strand
From NCBI annotation of GRCm38

  30229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10236  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ap1ar

Human
homologs
Human Homolog AP1AR, adaptor-related protein complex 1 associated regulatory protein
NCBI Gene ID 55435
neXtProt AC  NX_Q63HQ0
Human Synonyms  2C18, C4orf16, gamma-BAR, GBAR
Human Chr (Location)  4q25; chr4:112231737-112270055 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Interactions
Ap1ar interacts with 204 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cellular protein localization, negative regulation of cell motility, ...
Component cytoplasm, endosome, ...
Function AP-1 adaptor complex binding, Arp2/3 complex binding, ...
External Resources: FuncBase
Expression
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) cDNA(64)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000074238 (Evidence)
Entrez Gene211556 (Evidence)
UniGene403486
DFCITC1584213, TC1603663, TC1626649, TC1644868, TC1774763
Consensus CDS ProjectCCDS38629.1
International Mouse Knockout Project StatusAp1ar
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 211556 NCBI Gene Model | MGI Sequence Detail 30229 C57BL/6J ±  kb
transcript NM_145964 RefSeq | MGI Sequence Detail 2391 Not Specified 
polypeptide NP_666076 RefSeq | MGI Sequence Detail 298 Not Specified 

For the selected sequences
All sequences(47) RefSeq(18) UniProt(2)
Polymorphisms SNPs within 2kb(397 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000031857 AP-1 complex-associated regulatory protein
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:185589 Maritzen T, et al., Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10382-7
All references(29)
Other
accession IDs
MGI:2139553, MGI:2140060

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory