About   Help   FAQ
Kcnj14
Gene Detail
 Symbol
Name
ID
Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
MGI:2384820
Synonyms A930026G01Rik, IRK4, Kir2.4, MGC:25490, MGC:38951
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:45816467-45824747 bp, - strand
From NCBI annotation of GRCm38

  8281 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27086  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: G protein-activated inward rectifier potassium channel
Gene Tree: Kcnj14

Human
homologs
Human Homolog KCNJ14, potassium inwardly-rectifying channel, subfamily J, member 14
NCBI Gene ID 3770
neXtProt AC  NX_Q9UNX9
Human Synonyms  IRK4, KIR2.4
Human Chr (Location)  19q13; chr19:48455707-48466110 (+)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component dendrite, integral component of membrane, ...
Function inward rectifier potassium channel activity, voltage-gated ion channel activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (371)    Tissues (43)    Images (51)
Theiler Stages: 23, 25, 28
Assay TypeResults
RNA in situ 369
RT-PCR 2
cDNA source data(26)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000058743 (Evidence)
Entrez Gene211480 (Evidence)
UniGene68170
DFCITC1581740
DoTSDT.101154789, DT.94266161
NIA Mouse Gene IndexU057287, U129479
Consensus CDS ProjectCCDS21265.1
International Mouse Knockout Project StatusKcnj14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 211480 NCBI Gene Model | MGI Sequence Detail 8281 C57BL/6J ±  kb
transcript NM_145963 RefSeq | MGI Sequence Detail 2639 C57BL/6 
polypeptide Q8JZN3 UniProt | EBI | MGI Sequence Detail 434 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR016449 Potassium channel, inwardly rectifying, Kir
InterPro IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Protein Ontology PR:000001982 ATP-sensitive inward rectifier potassium channel 14
Graphical View of Protein Domain Structure
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:203518 Sulaiman P, et al., Kir2.4 surface expression and basal current are affected by heterotrimeric G-proteins. J Biol Chem. 2013 Mar 8;288(10):7420-9
All references(29)
Other
accession IDs
MGI:2444193

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory