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Kcnj14 Gene Detail
Summary
  • Symbol
    Kcnj14
  • Name
    potassium inwardly-rectifying channel, subfamily J, member 14
  • Synonyms
    A930026G01Rik, IRK4, Kir2.4, MGC:25490, MGC:38951
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384820
    NCBI Gene: 211480
  • Gene Overview
    MyGene.info: KCNJ14
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45816447-45824747 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384820
protein coding gene Chr7:45816447-45824782 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032249
protein coding gene Chr7:46137659-46146640 (-)
A/J MGP_AJ_G0032228
protein coding gene Chr7:45215359-45223498 (-)
AKR/J MGP_AKRJ_G0032164
protein coding gene Chr7:46485535-46494651 (-)
BALB/cJ MGP_BALBcJ_G0032240
protein coding gene Chr7:45213353-45223123 (-)
C3H/HeJ MGP_C3HHeJ_G0031955
protein coding gene Chr7:46968220-46978330 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032732
protein coding gene Chr7:48397578-48411541 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029746
protein coding gene Chr7:47765789-47773911 (-)
CAST/EiJ MGP_CASTEiJ_G0031283
protein coding gene Chr7:38413750-38422023 (-)
CBA/J MGP_CBAJ_G0031920
protein coding gene Chr7:50020385-50028998 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0032029
protein coding gene Chr7:44669859-44679462 (-)
LP/J MGP_LPJ_G0032156
protein coding gene Chr7:46843017-46853962 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032066
protein coding gene Chr7:48686578-48704636 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016274
protein coding gene Chr1:7946442-7954017 (+)
PWK/PhJ MGP_PWKPhJ_G0031006
protein coding gene Chr7:38265319-38273560 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030844
protein coding gene Chr7:33721792-33729970 (-)
WSB/EiJ MGP_WSBEiJ_G0031401
protein coding gene Chr7:46187135-46195886 (-)



Homology
more
  • Human Ortholog
    KCNJ14, potassium voltage-gated channel subfamily J member 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNJ14, potassium voltage-gated channel subfamily J member 14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IRK4, KIR2.4
  • Links
    NCBI Gene ID: 3770
    neXtProt AC: NX_Q9UNX9
    UniProt: Q9UNX9

  • Chr Location
    19q13.33; chr19:48455707-48466110 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211480 NCBI Gene Model | MGI Sequence Detail 8301 C57BL/6J ±  kb
transcript NM_145963 RefSeq | MGI Sequence Detail 2639 C57BL/6  
polypeptide Q8JZN3 UniProt | EBI | MGI Sequence Detail 434 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000001982 ATP-sensitive inward rectifier potassium channel 14
  • InterPro Domains
    IPR014756 Immunoglobulin E-set
    IPR016449 Potassium channel, inwardly rectifying, Kir
    IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Molecular
Reagents
less
  • All nucleic 29
    cDNA 28
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444193
References
more
  • Summaries
    All 32
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory