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Kcnj14 Gene Detail
Summary
  • Symbol
    Kcnj14
  • Name
    potassium inwardly-rectifying channel, subfamily J, member 14
  • Synonyms
    A930026G01Rik, IRK4, Kir2.4, MGC:25490, MGC:38951
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384820
    NCBI Gene: 211480
  • Gene Overview
    MyGene.info: KCNJ14
Location & Maps
more
  • Sequence Map
    Chr7:45816460-45824782 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8323 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.53 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KCNJ14, potassium voltage-gated channel subfamily J member 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNJ14, potassium voltage-gated channel subfamily J member 14
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IRK4, KIR2.4
  • Links
    NCBI Gene ID: 3770
    neXtProt AC: NX_Q9UNX9

  • Chr Location
    19q13; chr19:48455707-48466110 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059933 VEGA Gene Model | MGI Sequence Detail 8323 C57BL/6J ±  kb
transcript OTTMUST00000146827 VEGA | MGI Sequence Detail 2681 Not Applicable  
polypeptide OTTMUSP00000076381 VEGA | MGI Sequence Detail 434 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    130 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001982 ATP-sensitive inward rectifier potassium channel 14
  • InterPro Domains
    IPR014756 Immunoglobulin E-set
    IPR016449 Potassium channel, inwardly rectifying, Kir
    IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Molecular
Reagents
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  • All nucleic 28
    cDNA 27
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2444193
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:203518 Sulaiman P, et al., Kir2.4 surface expression and basal current are affected by heterotrimeric G-proteins. J Biol Chem. 2013 Mar 8;288(10):7420-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory