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Pla2g4b Gene Detail
Summary
  • Symbol
    Pla2g4b
  • Name
    phospholipase A2, group IVB (cytosolic)
  • Synonyms
    A030011C02Rik, MGC:28892
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384819
    NCBI Gene: 211429
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120033433-120043033 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    93 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384819
protein coding gene Chr2:120033417-120043033 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026358
protein coding gene Chr2:122888482-122898077 (+)
A/J MGP_AJ_G0026319
protein coding gene Chr2:117851769-117861368 (+)
AKR/J MGP_AKRJ_G0026298
protein coding gene Chr2:121140050-121149645 (+)
BALB/cJ MGP_BALBcJ_G0026332
protein coding gene Chr2:118090983-118100582 (+)
C3H/HeJ MGP_C3HHeJ_G0026078
protein coding gene Chr2:121605687-121616415 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026779
protein coding gene Chr2:126899725-126909338 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024159
protein coding gene Chr2:112872565-112882025 (+)
CAST/EiJ MGP_CASTEiJ_G0025540
protein coding gene Chr2:121923450-121933045 (+)
CBA/J MGP_CBAJ_G0026054
protein coding gene Chr2:131332771-131344949 (+)
DBA/2J MGP_DBA2J_G0026193
protein coding gene Chr2:117240637-117250236 (+)
FVB/NJ MGP_FVBNJ_G0026155
protein coding gene Chr2:116074953-116085728 (+)
LP/J MGP_LPJ_G0026294
protein coding gene Chr2:123146955-123156550 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026174
protein coding gene Chr2:135646657-135656252 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026834
protein coding gene Chr2:121262215-121271810 (+)
PWK/PhJ MGP_PWKPhJ_G0025276
protein coding gene Chr2:116838639-116848329 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025075
protein coding gene Chr2:120458140-120469233 (+)
WSB/EiJ MGP_WSBEiJ_G0025609
protein coding gene Chr2:122104281-122113876 (+)



Homology
more
  • Human Ortholog
    PLA2G4B, phospholipase A2 group IVB
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PLA2G4B, phospholipase A2 group IVB
    Orthology source: HGNC, HomoloGene
  • Synonyms
    cPLA2-beta, HsT16992
  • Links
    NCBI Gene ID: 100137049
    neXtProt AC: NX_P0C869
    UniProt: P0C869

  • Chr Location
    15q15.1; chr15:41838813-41848148 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 211429 NCBI Gene Model | MGI Sequence Detail 9601 C57BL/6J ±  kb
transcript NM_145378 RefSeq | MGI Sequence Detail 3859 C57BL/6  
polypeptide NP_663353 RefSeq | MGI Sequence Detail 791 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2685859
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory