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Wfdc5 Gene Detail
Summary
  • Symbol
    Wfdc5
  • Name
    WAP four-disulfide core domain 5
  • Synonyms
    PRG5, WAP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384800
    NCBI Gene: 209232
  • Gene Overview
    MyGene.info: WFDC5
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164176327-164182742 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 84.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384800
protein coding gene Chr2:164176325-164182742 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026838
protein coding gene Chr2:169569940-169577743 (-)
A/J MGP_AJ_G0026804
protein coding gene Chr2:162700313-162706724 (-)
AKR/J MGP_AKRJ_G0026775
protein coding gene Chr2:167523174-167529593 (-)
BALB/cJ MGP_BALBcJ_G0026813
protein coding gene Chr2:163042984-163049471 (-)
C3H/HeJ MGP_C3HHeJ_G0026555
protein coding gene Chr2:167877285-167883708 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027261
protein coding gene Chr2:174502694-174509200 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024631
protein coding gene Chr2:156011929-156018414 (-)
CAST/EiJ MGP_CASTEiJ_G0026016
protein coding gene Chr2:168300053-168309085 (-)
CBA/J MGP_CBAJ_G0026532
protein coding gene Chr2:180788468-180794941 (-)
DBA/2J MGP_DBA2J_G0026670
protein coding gene Chr2:161870091-161876510 (-)
FVB/NJ MGP_FVBNJ_G0026636
protein coding gene Chr2:160248291-160254708 (-)
LP/J MGP_LPJ_G0026773
protein coding gene Chr2:169669146-169677464 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026658
protein coding gene Chr2:184451628-184458076 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027317
protein coding gene Chr2:167423520-167429947 (-)
PWK/PhJ MGP_PWKPhJ_G0025750
protein coding gene Chr2:161448597-161455061 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025553
protein coding gene Chr2:166297687-166305839 (-)
WSB/EiJ MGP_WSBEiJ_G0026086
protein coding gene Chr2:168288859-168295273 (-)



Homology
more
  • Human Ortholog
    WFDC5, WAP four-disulfide core domain 5
  • Vertebrate Orthologs
    7
  • Human Ortholog
    WFDC5, WAP four-disulfide core domain 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ211D12.5, PRG5, WAP1
  • Links
    NCBI Gene ID: 149708
    neXtProt AC: NX_Q8TCV5
    UniProt: Q8TCV5

  • Chr Location
    20q13.12; chr20:45109452-45116321 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040154 Ensembl Gene Model | MGI Sequence Detail 6416 C57BL/6J ±  kb
transcript ENSMUST00000045127 Ensembl | MGI Sequence Detail 2322 Not Applicable  
polypeptide ENSMUSP00000035824 Ensembl | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR036645 Elafin-like superfamily
    IPR029714 WAP four-disulfide core domain protein 5
    IPR008197 WAP-type 'four-disulfide core' domain
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Phenotypes 4
  • Earliest
    J:99265 Clauss A, et al., The evolution of a genetic locus encoding small serine proteinase inhibitors. Biochem Biophys Res Commun. 2005 Jul 29;333(2):383-9
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory