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Akr1d1 Gene Detail
Summary
  • Symbol
    Akr1d1
  • Name
    aldo-keto reductase family 1, member D1
  • Synonyms
    MGC:25814
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384785
    NCBI Gene: 208665
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:37530173-37568815 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 16.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    115 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384785
protein coding gene Chr6:37529978-37574934 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030577
protein coding gene Chr6:35758847-35798530 (+)
A/J MGP_AJ_G0030550
protein coding gene Chr6:34227706-34262021 (+)
AKR/J MGP_AKRJ_G0030477
protein coding gene Chr6:35331452-35365898 (+)
BALB/cJ MGP_BALBcJ_G0030560
protein coding gene Chr6:34419574-34456191 (+)
C3H/HeJ MGP_C3HHeJ_G0030273
protein coding gene Chr6:35328802-35363741 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031014
protein coding gene Chr6:36659606-36710244 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028226
protein coding gene Chr6:32144245-32181675 (+)
CAST/EiJ MGP_CASTEiJ_G0029675
protein coding gene Chr6:35169492-35205969 (+)
CBA/J MGP_CBAJ_G0030251
protein coding gene Chr6:38056003-38094271 (+)
DBA/2J MGP_DBA2J_G0030395
protein coding gene Chr6:34060938-34095248 (+)
FVB/NJ MGP_FVBNJ_G0030349
protein coding gene Chr6:33848617-33885014 (+)
LP/J MGP_LPJ_G0030482
protein coding gene Chr6:35828588-35865519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030385
protein coding gene Chr6:40460288-40498737 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031044
protein coding gene Chr6:35237212-35273118 (+)
PWK/PhJ MGP_PWKPhJ_G0029389
protein coding gene Chr6:33689761-33726076 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029225
protein coding gene Chr6:34923162-34961862 (+)
WSB/EiJ MGP_WSBEiJ_G0029751
protein coding gene Chr6:35174274-35212222 (+)



Homology
more
  • Human Ortholog
    AKR1D1, aldo-keto reductase family 1 member D1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AKR1D1, aldo-keto reductase family 1 member D1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    3o5bred, CBAS2, SRD5B1
  • Links
    NCBI Gene ID: 6718
    neXtProt AC: NX_P51857
    UniProt: P51857

  • Chr Location
    7q33; chr7:138076432-138118304 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human AKR1D1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038641 Ensembl Gene Model | MGI Sequence Detail 38643 C57BL/6J ±  kb
transcript ENSMUST00000040987 Ensembl | MGI Sequence Detail 2699 Not Applicable  
polypeptide ENSMUSP00000048830 Ensembl | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:82195 Vergnes L, et al., A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res. 2003 Mar;44(3):503-11
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory