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Akr1d1
Gene Detail
Symbol

Name
ID
Akr1d1
aldo-keto reductase family 1, member D1
MGI:2384785
Synonyms
MGC:25814
Feature Type
protein coding gene
Genetic Map
Chromosome 6
16.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:37530173-37568815 bp, + strand
From VEGA annotation of GRCm38

  38643 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55943  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: AKR1D1
Protein SuperFamily: AKR
Gene Tree: Akr1d1

Human
homologs
AKR1D1, aldo-keto reductase family 1, member D1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6718
neXtProt AC: NX_P51857

Human Synonyms: 3o5bred, CBAS2, SRD5B1

Human Chr (Location): 7q32-q33; chr7:138076432-138118304 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human AKR1D1

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Akr1d1 interacts with 213 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase akr1d1    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000022180 (Evidence)
Ensembl Gene Model ENSMUSG00000038641 (Evidence)
Entrez Gene 208665 (Evidence)
UniGene 262635
DFCI TC1670494, TC1587808
DoTS DT.55114421
NIA Mouse Gene Index U317295, U006680
EC 1.3.1.3
Consensus CDS Project CCDS20007.1
International Mouse Phenotyping Consortium Status Akr1d1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022180 VEGA Gene Model | MGI Sequence Detail 38643 C57BL/6J ±  kb
transcript OTTMUST00000052668 VEGA | MGI Sequence Detail 2699 Not Applicable 
polypeptide OTTMUSP00000025008 VEGA | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(12) UniProt(2)
Polymorphisms
SNPs within 2kb(116 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001395 Aldo/keto reductase
InterPro IPR018170 Aldo/keto reductase, conserved site
InterPro IPR020471 Aldo/keto reductase subgroup
InterPro IPR023210 NADP-dependent oxidoreductase domain
Protein Ontology PR:000003907 3-oxo-5-beta-steroid 4-dehydrogenase
References
(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory