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Akr1d1
Gene Detail
 Symbol
Name
ID
Akr1d1
aldo-keto reductase family 1, member D1
MGI:2384785
Synonyms MGC:25814
Feature Type protein coding gene
Genetic Map
Chromosome 6
16.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:37530173-37568815 bp, + strand
From VEGA annotation of GRCm38

  38643 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55943  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: AKR
Gene Tree: Akr1d1

Human
homologs
Human Homolog AKR1D1, aldo-keto reductase family 1, member D1
NCBI Gene ID 6718
neXtProt AC  NX_P51857
Human Synonyms  3o5bred, CBAS2, SRD5B1
Human Chr (Location)  7q32-q33; chr7:138076432-138118304 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AKR1D1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Akr1d1 interacts with 214 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process androgen metabolic process, bile acid biosynthetic process, ...
Component cytoplasm, cytosol, ...
Function 3-oxo-5-beta-steroid 4-dehydrogenase activity, delta4-3-oxosteroid 5beta-reductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (3)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000022180 (Evidence)
Ensembl Gene ModelENSMUSG00000038641 (Evidence)
Entrez Gene208665 (Evidence)
UniGene262635
DFCITC1587808, TC1670494
DoTSDT.55114421
NIA Mouse Gene IndexU006680, U317295
EC1.3.1.3
Consensus CDS ProjectCCDS20007.1
International Mouse Knockout Project StatusAkr1d1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022180 VEGA Gene Model | MGI Sequence Detail 38643 C57BL/6J ±  kb
transcript OTTMUST00000052668 VEGA | MGI Sequence Detail 2699 Not Applicable 
polypeptide OTTMUSP00000025008 VEGA | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(116 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001395 Aldo/keto reductase
InterPro IPR018170 Aldo/keto reductase, conserved site
InterPro IPR020471 Aldo/keto reductase subgroup
InterPro IPR023210 NADP-dependent oxidoreductase domain
Protein Ontology PR:000003907 3-oxo-5-beta-steroid 4-dehydrogenase
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory