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Alg1
Gene Detail
 Symbol
Name
ID
Alg1
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
MGI:2384774
Synonyms HMAT1, HMT1, MGC:18946
Feature Type protein coding gene
Genetic Map
Chromosome 16
2.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:5233621-5244912 bp, + strand
From VEGA annotation of GRCm38

  11292 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5387  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: chitobiosyldiphosphodolichol beta-mannosyltransferase
Gene Tree: Alg1

Human
homologs
Human Homolog ALG1, ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
NCBI Gene ID 56052
neXtProt AC  NX_Q9BT22
Human Synonyms  CDG1K, hMat-1, HMAT1, HMT1, HMT-1, Mat-1, MT-1
Human Chr (Location)  16p13.3; chr16:5071809-5087379 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG1
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Interactions
Alg1 interacts with 74 markers (Mir22, Mir125b-2, Mir194-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process biological_process
Component endoplasmic reticulum, integral component of membrane, ...
Function chitobiosyldiphosphodolichol beta-mannosyltransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000028464 (Evidence)
Ensembl Gene ModelENSMUSG00000039427 (Evidence)
Entrez Gene208211 (Evidence)
NIA Mouse Gene IndexU016773
EC2.4.1.142
Consensus CDS ProjectCCDS49753.1
International Mouse Knockout Project StatusAlg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028464 VEGA Gene Model | MGI Sequence Detail 11292 C57BL/6J ±  kb
transcript OTTMUST00000070544 VEGA | MGI Sequence Detail 1755 Not Applicable 
polypeptide OTTMUSP00000035973 VEGA | MGI Sequence Detail 482 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(112 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026051 Asparagine-linked glycosylation protein 1-like
Protein Ontology PR:000003937 chitobiosyldiphosphodolichol beta-mannosyltransferase
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory