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Cdc42ep3 Gene Detail
Summary
  • Symbol
    Cdc42ep3
  • Name
    CDC42 effector protein (Rho GTPase binding) 3
  • Synonyms
    3200001F04Rik, Borg2, Cep3, UB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384718
    NCBI Gene: 260409
  • Gene Overview
    MyGene.info: CDC42EP3
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:79333727-79355091 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.30 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384718
 protein coding gene Chr17:79333946-79355825 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024050
 protein coding gene Chr17:82190328-82211521 (-)
A/J MGP_AJ_G0024007
 protein coding gene Chr17:79664014-79685145 (-)
AKR/J MGP_AKRJ_G0023976
 protein coding gene Chr17:80875808-80896943 (-)
BALB/cJ MGP_BALBcJ_G0024009
 protein coding gene Chr17:79530922-79552050 (-)
C3H/HeJ MGP_C3HHeJ_G0023773
 protein coding gene Chr17:81781709-81802902 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024453
 protein coding gene Chr17:85180993-85202059 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021895
 protein coding gene Chr17:75070446-75091621 (-)
CAST/EiJ MGP_CASTEiJ_G0023253
 protein coding gene Chr17:82414012-82435160 (-)
CBA/J MGP_CBAJ_G0023747
 protein coding gene Chr17:88730425-88751618 (-)
DBA/2J MGP_DBA2J_G0023876
 protein coding gene Chr17:78186463-78210711 (-)
FVB/NJ MGP_FVBNJ_G0023842
 protein coding gene Chr17:77699308-77720501 (-)
LP/J MGP_LPJ_G0023959
 protein coding gene Chr17:83036595-83057788 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023870
 protein coding gene Chr17:88822475-88844663 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024498
 protein coding gene Chr17:81358903-81380096 (-)
PWK/PhJ MGP_PWKPhJ_G0022999
 protein coding gene Chr17:77694607-77715900 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022810
 protein coding gene Chr17:78145740-78166928 (-)
WSB/EiJ MGP_WSBEiJ_G0023320
 protein coding gene Chr17:82189574-82210699 (-)



Homology
more
  • Human Ortholog
    CDC42EP3, CDC42 effector protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDC42EP3, CDC42 effector protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BORG2, CEP3, UB1
  • Links
    NCBI Gene ID: 10602
    neXtProt AC: NX_Q9UKI2
    UniProt: Q9UKI2

  • Chr Location
    2p22.2; chr2:37641882-37672535 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    44
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036533 Ensembl Gene Model | MGI Sequence Detail 21365 C57BL/6J ±  kb
transcript ENSMUST00000068958 Ensembl | MGI Sequence Detail 2265 Not Applicable  
polypeptide ENSMUSP00000067217 Ensembl | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915275, MGI:2146788
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65159 Joberty G, et al., The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. Mol Cell Biol. 1999 Oct;19(10):6585-97
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/15/2019
MGI 6.13 		The Jackson Laboratory