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Ndrg4
Gene Detail
 Symbol
Name
ID
Ndrg4
N-myc downstream regulated gene 4
MGI:2384590
Synonyms D8Bwg1337e, MGC:7067, Ndr1-rs, Ndr4, SMAP-8
Feature Type protein coding gene
Genetic Map
Chromosome 8
47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:95676980-95715119 bp, + strand
From VEGA annotation of GRCm38

  38140 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ndrg4

Human
homologs
Human Homolog NDRG4, NDRG family member 4
NCBI Gene ID 65009
neXtProt AC  NX_Q9ULP0
Human Synonyms  BDM1, SMAP8, SMAP-8
Human Chr (Location)  16q21-q22.1; chr16:58463645-58513619 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit spatial learning deficits and increased susceptibility to ischemic brain injury.
 
Interactions
Ndrg4 interacts with 387 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process positive regulation of neuron projection development
Component cytoplasm, endoplasmic reticulum membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (297)    Tissues (143)    Images (44)
Theiler Stages: 1, 2, 3, 5, 16, 17, 19, 20, 21, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 287
RT-PCR 10
cDNA source data(125)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(129) cDNA(126) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000027408 (Evidence)
Ensembl Gene ModelENSMUSG00000036564 (Evidence)
Entrez Gene234593 (Evidence)
UniGene29846
DFCITC1572927, TC1587160
DoTSDT.101131251, DT.101313789, DT.531205, DT.99858062
NIA Mouse Gene IndexU009694
Consensus CDS ProjectCCDS22565.1, CCDS57634.1
International Mouse Knockout Project StatusNdrg4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027408 VEGA Gene Model | MGI Sequence Detail 38140 C57BL/6J ±  kb
transcript OTTMUST00000067797 VEGA | MGI Sequence Detail 3101 Not Applicable 
polypeptide OTTMUSP00000034174 VEGA | MGI Sequence Detail 404 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(234 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004142 Ndr
Protein Ontology PR:000011062 protein NDRG4
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
All references(43)
Other
accession IDs
MGD-MRK-34121, MGD-MRK-37557, MGI:106427, MGI:108513, MGI:2142896

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory