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Tti2 Gene Detail
Summary
  • Symbol
    Tti2
  • Name
    TELO2 interacting protein 2
  • Synonyms
    BC019943, MGC:28346
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384576
    NCBI Gene: 234138
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:31150316-31164703 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 18.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384576
protein coding gene Chr8:31150315-31164703 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033514
protein coding gene Chr8:29539480-29553130 (+)
A/J MGP_AJ_G0033494
protein coding gene Chr8:28376839-28391450 (+)
AKR/J MGP_AKRJ_G0033418
protein coding gene Chr8:29310190-29325055 (+)
BALB/cJ MGP_BALBcJ_G0033490
protein coding gene Chr8:28525812-28539480 (+)
C3H/HeJ MGP_C3HHeJ_G0033204
protein coding gene Chr8:29604492-29618461 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034006
protein coding gene Chr8:30609556-30637284 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030956
protein coding gene Chr8:25266771-25280133 (+)
CAST/EiJ MGP_CASTEiJ_G0032529
protein coding gene Chr8:28986272-29000288 (+)
CBA/J MGP_CBAJ_G0033180
protein coding gene Chr8:31853341-31869144 (+)
DBA/2J MGP_DBA2J_G0033333
protein coding gene Chr8:28375040-28388713 (+)
FVB/NJ MGP_FVBNJ_G0033278
protein coding gene Chr8:28094807-28108373 (+)
LP/J MGP_LPJ_G0033423
protein coding gene Chr8:29482766-29498198 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033320
protein coding gene Chr8:31434587-31449510 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034025
protein coding gene Chr8:29321967-29336159 (+)
PWK/PhJ MGP_PWKPhJ_G0032241
protein coding gene Chr8:27889348-27904405 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032074
protein coding gene Chr8:28661137-28675028 (+)
WSB/EiJ MGP_WSBEiJ_G0032645
protein coding gene Chr8:29489906-29503487 (+)



Homology
more
  • Human Ortholog
    TTI2, TELO2 interacting protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TTI2, TELO2 interacting protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C8orf41, MRT39
  • Links
    NCBI Gene ID: 80185
    neXtProt AC: NX_Q6NXR4
    UniProt: Q6NXR4

  • Chr Location
    8p12; chr8:33498509-33513601 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11836
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TTI2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human TTI2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234138 NCBI Gene Model | MGI Sequence Detail 14388 C57BL/6J ±  kb
transcript NR_103719 RefSeq | MGI Sequence Detail 5059 C57BL/6  
polypeptide Q8BGV4 UniProt | EBI | MGI Sequence Detail 512 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 6
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory