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Plppr2 Gene Detail
Summary
  • Symbol
    Plppr2
  • Name
    phospholipid phosphatase related 2
  • Synonyms
    BC018242, Lppr2, MGC:25492, PRG-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384575
    NCBI Gene: 235044
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21937033-21948907 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384575
protein coding gene Chr9:21936425-21948907 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034468
protein coding gene Chr9:19209364-19223842 (+)
A/J MGP_AJ_G0034446
protein coding gene Chr9:18836984-18848779 (+)
AKR/J MGP_AKRJ_G0034373
protein coding gene Chr9:19205932-19217836 (+)
BALB/cJ MGP_BALBcJ_G0034437
protein coding gene Chr9:18720098-18733046 (+)
C3H/HeJ MGP_C3HHeJ_G0034149
protein coding gene Chr9:19502159-19514299 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034958
protein coding gene Chr9:19961967-19977875 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031888
protein coding gene Chr9:17940959-17952752 (+)
CAST/EiJ MGP_CASTEiJ_G0033472
protein coding gene Chr9:19339846-19354196 (+)
CBA/J MGP_CBAJ_G0034122
protein coding gene Chr9:20749921-20764498 (+)
DBA/2J MGP_DBA2J_G0034281
protein coding gene Chr9:18804019-18816503 (+)
FVB/NJ MGP_FVBNJ_G0034224
protein coding gene Chr9:18353118-18365379 (+)
LP/J MGP_LPJ_G0034366
protein coding gene Chr9:19352399-19368523 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034267
protein coding gene Chr9:22308817-22323513 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034978
protein coding gene Chr9:19160415-19175417 (+)
PWK/PhJ MGP_PWKPhJ_G0033177
protein coding gene Chr9:18806658-18819080 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033012
protein coding gene Chr9:19212609-19223082 (+)
WSB/EiJ MGP_WSBEiJ_G0033587
protein coding gene Chr9:18891414-18905119 (+)



Homology
more
  • Human Ortholog
    PLPPR2, phospholipid phosphatase related 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PLPPR2, phospholipid phosphatase related 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LPPR2, PRG4
  • Links
    NCBI Gene ID: 64748
    neXtProt AC: NX_Q96GM1
    UniProt: Q96GM1

  • Chr Location
    19p13.2; chr19:11355386-11365698 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040563 Ensembl Gene Model | MGI Sequence Detail 11875 C57BL/6J ±  kb
transcript ENSMUST00000046371 Ensembl | MGI Sequence Detail 2626 Not Applicable  
polypeptide ENSMUSP00000038616 Ensembl | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009904 phospholipid phosphatase-related protein type 2
  • EC
  • InterPro Domains
    IPR028679 Lipid phosphate phosphatase-related protein type 2
    IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
    IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Molecular
Reagents
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  • All nucleic 31
    cDNA 30
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:89819 Savaskan NE, et al., Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family. Eur J Neurosci. 2004 Jan;19(1):212-20
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory