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Klhdc4 Gene Detail
Summary
  • Symbol
    Klhdc4
  • Name
    kelch domain containing 4
  • Synonyms
    G430025P05Rik, MGC:19372
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384569
    NCBI Gene: 234825
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:122523052-122556308 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 70.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    600 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384569
protein coding gene Chr8:122523047-122556322 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034216
protein coding gene Chr8:125326240-125356939 (-)
A/J MGP_AJ_G0034196
protein coding gene Chr8:120120965-120152804 (-)
AKR/J MGP_AKRJ_G0034123
protein coding gene Chr8:123642704-123673878 (-)
BALB/cJ MGP_BALBcJ_G0034190
protein coding gene Chr8:120325355-120354089 (-)
C3H/HeJ MGP_C3HHeJ_G0033901
protein coding gene Chr8:124343217-124371496 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034710
protein coding gene Chr8:129501964-129529621 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031652
protein coding gene Chr8:112955628-112987089 (-)
CAST/EiJ MGP_CASTEiJ_G0033228
protein coding gene Chr8:124393289-124422563 (-)
CBA/J MGP_CBAJ_G0033874
protein coding gene Chr8:134266487-134294234 (-)
DBA/2J MGP_DBA2J_G0034030
protein coding gene Chr8:119313316-119341423 (-)
FVB/NJ MGP_FVBNJ_G0033973
protein coding gene Chr8:118432992-118461980 (-)
LP/J MGP_LPJ_G0034119
protein coding gene Chr8:125455254-125483082 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034020
protein coding gene Chr8:136485751-136518735 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034728
protein coding gene Chr8:123815175-123845705 (-)
PWK/PhJ MGP_PWKPhJ_G0032930
protein coding gene Chr8:119128657-119155552 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032770
protein coding gene Chr8:122532260-122558252 (-)
WSB/EiJ MGP_WSBEiJ_G0033344
protein coding gene Chr8:124570105-124602548 (-)



Homology
more
  • Human Ortholog
    KLHDC4, kelch domain containing 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHDC4, kelch domain containing 4
  • Links
    NCBI Gene ID: 54758
    neXtProt AC: NX_Q8TBB5
    UniProt: Q8TBB5

  • Chr Location
    16q24.2; chr16:87693537-87765997 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040263 Ensembl Gene Model | MGI Sequence Detail 33257 C57BL/6J ±  kb
transcript ENSMUST00000045884 Ensembl | MGI Sequence Detail 2078 Not Applicable  
polypeptide ENSMUSP00000043439 Ensembl | MGI Sequence Detail 584 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 5
Other
Accession IDs
less
MGI:1889338, MGI:2142740
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:282947 Poncet N, et al., Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos. EMBO Rep. 2020 Jan 7;21(1):e48469

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory