Rgs9bp
Gene Detail

Symbol Name ID

Rgs9bp regulator of G-protein signalling 9 binding protein MGI:2384418

Synonyms

R9AP, Rgs9-1bp

Feature Type

protein coding gene

Genetic Map

Chromosome 7

21.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:35578998-35585582 bp, - strand From Ensembl annotation of GRCm38   6585 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:17113  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rgs9bp

Human homologs

Human Homolog		RGS9BP, regulator of G protein signaling 9 binding protein
NCBI Gene ID		388531
neXtProt AC		NX_Q6ZS82
Human Synonyms		PERRS, R9AP, RGS9
Human Chr (Location)		19q13.11; chr19:33166313-33169206 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RGS9BP

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

In spite of normal retinal morphology, rod light response is impaired in homozygous mutant mice.

 

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	detection of light stimulus involved in visual perception, negative regulation of signal transduction, ...
Component	integral to membrane, membrane

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (8)    Images (11)
Theiler Stages: 20, 22, 24, 26, 28

Assay Type	Results
RNA in situ	14

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(26) cDNA(26)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000056043 (Evidence)
Entrez Gene	243923 (Evidence)
UniGene	222680
DFCI	TC1650064, TC1657703
DoTS	DT.99841149
NIA Mouse Gene Index	U028440
Consensus CDS Project	CCDS21153.1
International Mouse Knockout Project Status	Rgs9bp

Sequences

Length	Strain/Species
genomic	ENSMUSG00000056043	Ensembl Gene Model | MGI Sequence Detail	6585	C57BL/6J
transcript	ENSMUST00000069912	Ensembl | MGI Sequence Detail	6585	Not Applicable
polypeptide	ENSMUSP00000065511	Ensembl | MGI Sequence Detail	237	Not Applicable

All sequences(16) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(13 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026513	Regulator of G-protein signalling 9-binding protein
InterPro	IPR026512	RGS7BP/RGS9BP family
Protein Ontology	PR:000013966	regulator of G-protein signaling 9-binding protein

References

(Earliest) J:78055 Hu G, et al., R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9755-60
(Latest) J:190903 Umino Y, et al., The relationship between slow photoresponse recovery rate and temporal resolution of vision. J Neurosci. 2012 Oct 10;32(41):14364-73
All references(31)