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Usp11 Gene Detail
Summary
  • Symbol
    Usp11
  • Name
    ubiquitin specific peptidase 11
  • Synonyms
    6230415D12Rik, MGC:6649
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384312
    NCBI Gene: 236733
  • Gene Overview
    MyGene.info: USP11
Location & Maps
more
  • Sequence Map
    ChrX:20703906-20720539 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16634 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 16.20 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    USP11, ubiquitin specific peptidase 11
  • Vertebrate Orthologs
    7
  • Human Ortholog
    USP11, ubiquitin specific peptidase 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    UHX1
  • Links
    NCBI Gene ID: 8237
    neXtProt AC: NX_P51784

  • Chr Location
    Xp11.23; chrX:47232915-47248328 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Gene trapped
    9
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017158 VEGA Gene Model | MGI Sequence Detail 16634 C57BL/6J ±  kb
transcript OTTMUST00000041524 VEGA | MGI Sequence Detail 3467 Not Applicable  
polypeptide OTTMUSP00000018659 VEGA | MGI Sequence Detail 921 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000017147 ubiquitin carboxyl-terminal hydrolase 11
  • EC
  • InterPro Domains
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
    IPR028135 Ubiquitin-like domain, USP-type
    IPR018200 Ubiquitin specific protease, conserved site
    IPR028889 Ubiquitin specific protease domain
Molecular
Reagents
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  • All nucleic 74
    cDNA 74

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444517
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:213512 Werber M, et al., The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development. 2014 Jun;141(11):2325-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory