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Nav3 Gene Detail
Summary
  • Symbol
    Nav3
  • Name
    neuron navigator 3
  • Synonyms
    4732483H20Rik, 9630020C08Rik, mKIAA0938, POMFIL1, Pomfil1p, steerin 3, unc53H3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183703
    NCBI Gene: 260315
Location & Maps
more
  • Sequence Map
    Chr10:109682660-110456204 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      773545 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 57.18 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    NAV3, neuron navigator 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NAV3, neuron navigator 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    POMFIL1, STEERIN3, unc53H3
  • Links
    NCBI Gene ID: 89795
    neXtProt AC: NX_Q8IVL0

  • Chr Location
    12q21.2; chr12:77571862-78213012 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 56688
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: NAV3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Nav3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034560 VEGA Gene Model | MGI Sequence Detail 773545 C57BL/6J ±  kb
transcript OTTMUST00000087675 VEGA | MGI Sequence Detail 8561 Not Applicable  
polypeptide OTTMUSP00000047720 VEGA | MGI Sequence Detail 2366 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    8520 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011008 neuron navigator 3
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003959 ATPase, AAA-type, core
    IPR001715 Calponin homology domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
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MGI:2442779, MGI:3041169
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:77366 Coy JF, et al., Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene. 2002 May 15;290(1-2):73-94
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory