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Cytip
Gene Detail
 Symbol
Name
ID
Cytip
cytohesin 1 interacting protein
MGI:2183535
Synonyms A130053M09Rik, Cbp, Cybr, Pscdbp
Feature Type protein coding gene
Genetic Map
Chromosome 2
33.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:58129137-58195532 bp, - strand
From VEGA annotation of GRCm38

  66396 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3167  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cytip

Human
homologs
Human Homolog CYTIP, cytohesin 1 interacting protein
NCBI Gene ID 9595
neXtProt AC  NX_O60759
Human Synonyms  B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP
Human Chr (Location)  2q11.2; chr2:157414619-157444092 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele display impaired trafficking and/or cell adhesion of immune system cells. Mice homozygous for a reporter allele show normal immune cell development and function; however, mutant hematopoietic stems cells have impaired repopulating activity.
 
Interactions
Cytip interacts with 373 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process regulation of cell adhesion
Component cell cortex, cytoplasm, ...
External Resources: FuncBase
Expression
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000012676 (Evidence)
Ensembl Gene ModelENSMUSG00000026832 (Evidence)
Entrez Gene227929 (Evidence)
DFCITC1572611, TC1684122, TC1690056
DoTSDT.101191397, DT.101303486, DT.101402449, DT.110695921, DT.483177, DT.87069384
NIA Mouse Gene IndexU022650
Consensus CDS ProjectCCDS16048.1
International Mouse Knockout Project StatusCytip
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012676 VEGA Gene Model | MGI Sequence Detail 66396 C57BL/6J ±  kb
transcript OTTMUST00000030201 VEGA | MGI Sequence Detail 6110 Not Applicable 
polypeptide OTTMUSP00000013590 VEGA | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(499 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
Protein Ontology PR:000006157 cytohesin-interacting protein
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:187783 Heib V, et al., Cytip regulates dendritic-cell function in contact hypersensitivity. Eur J Immunol. 2012 Mar;42(3):589-97
All references(39)
Other
accession IDs
MGI:2138967, MGI:2139510, MGI:2444809

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory