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Dlgap5
Gene Detail
Symbol

Name
ID
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
MGI:2183453
Synonyms
C86398, Dlg7, Hurp, mKIAA0008
Feature Type
protein coding gene
Genetic Map
Chromosome 14
24.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:47387779-47418407 bp, - strand
From VEGA annotation of GRCm38

  30629 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8840  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dlgap5

Human
homologs
Human Homolog DLGAP5, discs, large (Drosophila) homolog-associated protein 5
NCBI Gene ID 9787
neXtProt AC  NX_Q15398
Human Synonyms  DLG7, HURP
Human Chr (Location)  14q22.3; chr14:55148116-55191678 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(11) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display female infertility resulting from a defect in decidualization.
 
Interactions
Dlgap5 interacts with 9 markers (Mir33, Mir194-1, Mir194-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell cycle, dephosphorylation, ...
Component cytoplasm, cytoskeleton, ...
Function phosphoprotein phosphatase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(98)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(98) cDNA(98)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000042413 (Evidence)
Ensembl Gene ModelENSMUSG00000037544 (Evidence)
Entrez Gene218977 (Evidence)
UniGene240543
DFCITC1577698, TC1587717, TC1597316, TC1756783
DoTSDT.97385751, DT.87068671, DT.101736139, DT.55192348, DT.40177963, DT.101736141
NIA Mouse Gene IndexU035473
Consensus CDS ProjectCCDS26987.1, CCDS49470.1
International Mouse Knockout Project StatusDlgap5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042413 VEGA Gene Model | MGI Sequence Detail 30629 C57BL/6J ±  kb
transcript OTTMUST00000111820 VEGA | MGI Sequence Detail 2964 Not Applicable 
polypeptide OTTMUSP00000062686 VEGA | MGI Sequence Detail 808 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(9) UniProt(9)
Polymorphisms
SNPs within 2kb(380 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005026 Guanylate-kinase-associated protein
Protein Ontology PR:000006520 disks large-associated protein 5
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:167991 Breuer M, et al., HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells. J Cell Biol. 2010 Dec 27;191(7):1251-60
All references(38)
Other
accession IDs
MGI:1353581, MGI:2145876

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory