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Agap3 Gene Detail
Summary
  • Symbol
    Agap3
  • Name
    ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
  • Synonyms
    Centg3, Crag, MGC:37541, MRIP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183446
    NCBI Gene: 213990
  • Gene Overview
    MyGene.info: AGAP3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:24452177-24502047 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 11.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    322 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183446
protein coding gene Chr5:24451886-24502047 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029346
protein coding gene Chr5:22184166-22237771 (+)
A/J MGP_AJ_G0029312
protein coding gene Chr5:21424813-21475625 (+)
AKR/J MGP_AKRJ_G0029263
protein coding gene Chr5:22286445-22338118 (+)
BALB/cJ MGP_BALBcJ_G0029323
protein coding gene Chr5:21938068-21989706 (+)
C3H/HeJ MGP_C3HHeJ_G0029043
protein coding gene Chr5:22401174-22454717 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029776
protein coding gene Chr5:23673671-23731790 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027014
protein coding gene Chr5:19367457-19417413 (+)
CAST/EiJ MGP_CASTEiJ_G0028455
protein coding gene Chr5:21574566-21631038 (+)
CBA/J MGP_CBAJ_G0029010
protein coding gene Chr5:24063110-24116999 (+)
DBA/2J MGP_DBA2J_G0029161
protein coding gene Chr5:21718374-21768946 (+)
FVB/NJ MGP_FVBNJ_G0029119
protein coding gene Chr5:21087272-21139612 (+)
LP/J MGP_LPJ_G0029245
protein coding gene Chr5:22585618-22638356 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029148
protein coding gene Chr5:25184600-25235171 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029810
protein coding gene Chr5:21930393-21987577 (+)
PWK/PhJ MGP_PWKPhJ_G0028179
protein coding gene Chr5:20794778-20849058 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028010
protein coding gene Chr5:21284261-21335932 (+)
WSB/EiJ MGP_WSBEiJ_G0028535
protein coding gene Chr5:21998804-22057180 (+)



Homology
more
  • Human Ortholog
    AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AGAP-3, CENTG3, cnt-g3, CRAG, MRIP-1
  • Links
    NCBI Gene ID: 116988
    neXtProt AC: NX_Q96P47
    UniProt: Q96P47

  • Chr Location
    7q36.1; chr7:151085831-151144436 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023353 Ensembl Gene Model | MGI Sequence Detail 49871 C57BL/6J ±  kb
transcript ENSMUST00000024123 Ensembl | MGI Sequence Detail 3207 Not Applicable  
polypeptide ENSMUSP00000024123 Ensembl | MGI Sequence Detail 910 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 74
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141107
References
more
  • Summaries
    All 39
    Diseases 1
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory