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Diras1
Gene Detail
 Symbol
Name
ID
Diras1
DIRAS family, GTP-binding RAS-like 1
MGI:2183442
Synonyms Di-Ras1, GBTS1
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:81019589-81025662 bp, - strand
From VEGA annotation of GRCm38

  6074 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64823  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: ras protein
Gene Tree: Diras1

Human
homologs
Human Homolog DIRAS1, DIRAS family, GTP-binding RAS-like 1
NCBI Gene ID 148252
neXtProt AC  NX_O95057
Human Synonyms  Di-Ras1, GBTS1, RIG
Human Chr (Location)  19p13.3; chr19:2714567-2721392 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Diras1 interacts with 207 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process GTP catabolic process, signal transduction, ...
Component membrane, plasma membrane
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (186)    Tissues (43)    Images (32)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 186
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000030296 (Evidence)
Ensembl Gene ModelENSMUSG00000043670 (Evidence)
Entrez Gene208666 (Evidence)
UniGene44995
DFCITC1580825
DoTSDT.99675872
NIA Mouse Gene IndexU032030
Consensus CDS ProjectCCDS24040.1
International Mouse Knockout Project StatusDiras1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030296 VEGA Gene Model | MGI Sequence Detail 6074 C57BL/6J ±  kb
transcript OTTMUST00000075002 VEGA | MGI Sequence Detail 2953 Not Applicable 
polypeptide OTTMUSP00000039245 VEGA | MGI Sequence Detail 198 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(7 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000006486 GTP-binding protein Di-Ras1
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory