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Diras1 Gene Detail
Summary
  • Symbol
    Diras1
  • Name
    DIRAS family, GTP-binding RAS-like 1
  • Synonyms
    Di-Ras1, GBTS1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183442
    NCBI Gene: 208666
Location & Maps
more
  • Sequence Map
    Chr10:81019589-81025662 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6074 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DIRAS1, DIRAS family, GTP-binding RAS-like 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    DIRAS1, DIRAS family, GTP-binding RAS-like 1
    Orthology source: HomoloGene
  • Synonyms
    Di-Ras1, GBTS1, RIG
  • Links
    NCBI Gene ID: 148252
    neXtProt AC: NX_O95057

  • Chr Location
    19p13.3; chr19:2714567-2721392 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    3
  • Genomic Mutations
    1 involving Diras1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030296 VEGA Gene Model | MGI Sequence Detail 6074 C57BL/6J ±  kb
transcript OTTMUST00000075002 VEGA | MGI Sequence Detail 2953 Not Applicable  
polypeptide OTTMUSP00000039245 VEGA | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    7 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000006486 GTP-binding protein Di-Ras1
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR020849 Small GTPase superfamily, Ras type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 4
    cDNA 4

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory