Psat1
Gene Detail

Symbol Name ID

Psat1 phosphoserine aminotransferase 1 MGI:2183441

Synonyms

D8Ertd814e, EPIP, PSA

Feature Type

protein coding gene

Genetic Map

Chromosome 19

10.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:15904678-15947337 bp, - strand From VEGA annotation of GRCm38   42660 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: phosphoserine aminotransferase
Gene Tree: Psat1

Human homologs

Human Homolog		PSAT1, phosphoserine aminotransferase 1
NCBI Gene ID		29968
neXtProt AC		NX_Q9Y617
Human Synonyms		EPIP, PSA, PSAT
Human Chr (Location)		9q21.2; chr9:80912059-80945009 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PSAT1

Alleles and phenotypes

All alleles(5) : Targeted(2) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	cellular amino acid biosynthetic process, L-serine biosynthetic process, ...
Function	catalytic activity, O-phospho-L-serine:2-oxoglutarate aminotransferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (207)    Tissues (113)    Images (36)
Theiler Stages: 15, 19, 22, 23

Assay Type	Results
RNA in situ	207

cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000030919 (Evidence)
Ensembl Gene Model	ENSMUSG00000024640 (Evidence)
Entrez Gene	107272 (Evidence)
DFCI	TC1573903, TC1595550, TC1645985, TC1708595
DoTS	DT.101394989, DT.101394991, DT.101394993, DT.102547171, DT.495237, DT.55258012, DT.97389703
NIA Mouse Gene Index	U038884
EC	2.6.1.52
Consensus CDS Project	CCDS29681.1, CCDS57139.1
International Mouse Knockout Project Status	Psat1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030919	VEGA Gene Model | MGI Sequence Detail	42660	C57BL/6J
transcript	OTTMUST00000076503	VEGA | MGI Sequence Detail	2617	Not Applicable
polypeptide	OTTMUSP00000040286	VEGA | MGI Sequence Detail	370	Not Applicable

All sequences(84) RefSeq(4) UniProt(7)

Polymorphisms

SNPs(121 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000192	Aminotransferase, class V/Cysteine desulfurase
InterPro	IPR020578	Aminotransferase class-V pyridoxal-phosphate binding site
InterPro	IPR022278	Phosphoserine aminotransferase
InterPro	IPR003248	Phosphoserine aminotransferase, subgroup
InterPro	IPR015424	Pyridoxal phosphate-dependent transferase, major domain
InterPro	IPR015421	Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro	IPR015422	Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Protein Ontology	PR:000013339	phosphoserine aminotransferase

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)

Other accession IDs

MGI:1289292, MGI:2147628, MGI:2147656, MGI:3034454