About   Help   FAQ
Psat1
Gene Detail
Symbol

Name
ID
Psat1
phosphoserine aminotransferase 1
MGI:2183441
Synonyms
D8Ertd814e, EPIP, PSA
Feature Type
protein coding gene
Genetic Map
Chromosome 19
10.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:15904678-15947337 bp, - strand
From VEGA annotation of GRCm38

  42660 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphoserine aminotransferase
Gene Tree: Psat1

Human
homologs
Human Homolog PSAT1, phosphoserine aminotransferase 1
NCBI Gene ID 29968
neXtProt AC  NX_Q9Y617
Human Synonyms  EPIP, NLS2, PSA, PSAT, PSATD
Human Chr (Location)  9q21.2; chr9:78297075-78330093 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human PSAT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
 
Mice homozygous for a knock-out allele exhibit craniofacial defects, exencephaly and growth retardation.
 
Interactions
Psat1 interacts with 182 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (207)    Tissues (113)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 207
cDNA source data(27)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000030919 (Evidence)
Ensembl Gene ModelENSMUSG00000024640 (Evidence)
Entrez Gene107272 (Evidence)
DFCITC1595550, TC1708595, TC1573903, TC1645985
DoTSDT.55258012, DT.101394989, DT.97389703, DT.102547171, DT.495237, DT.101394991, DT.101394993
NIA Mouse Gene IndexU038884
EC2.6.1.52
Consensus CDS ProjectCCDS29681.1, CCDS57139.1
International Mouse Knockout Project StatusPsat1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030919 VEGA Gene Model | MGI Sequence Detail 42660 C57BL/6J ±  kb
transcript OTTMUST00000076503 VEGA | MGI Sequence Detail 2617 Not Applicable 
polypeptide OTTMUSP00000040286 VEGA | MGI Sequence Detail 370 Not Applicable 

For the selected sequences
All sequences(92) RefSeq(6) UniProt(13)
Polymorphisms
SNPs within 2kb(403 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000192 Aminotransferase, class V/Cysteine desulfurase
InterPro IPR020578 Aminotransferase class-V pyridoxal-phosphate binding site
InterPro IPR022278 Phosphoserine aminotransferase
InterPro IPR003248 Phosphoserine aminotransferase, subgroup
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Protein Ontology PR:000013339 phosphoserine aminotransferase
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(42)
Other
accession IDs
MGI:1289292, MGI:2147628, MGI:2147656, MGI:3034454

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory