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Psat1
Gene Detail
 Symbol
Name
ID
Psat1
phosphoserine aminotransferase 1
MGI:2183441
Synonyms D8Ertd814e, EPIP, PSA
Feature Type protein coding gene
Genetic Map
Chromosome 19
10.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:15904678-15947337 bp, - strand
From VEGA annotation of GRCm38

  42660 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: phosphoserine aminotransferase
Gene Tree: Psat1

Human
homologs
Human Homolog PSAT1, phosphoserine aminotransferase 1
NCBI Gene ID 29968
neXtProt AC  NX_Q9Y617
Human Synonyms  EPIP, PSA, PSAT
Human Chr (Location)  9q21.2; chr9:78297075-78330093 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PSAT1
Alleles
and
phenotypes
All alleles(5) : Targeted(2) Gene trapped(3)
 
Mice homozygous for a knock-out allele exhibit craniofacial defects, exencephaly and growth retardation.
 
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular amino acid biosynthetic process, L-serine biosynthetic process, ...
Component extracellular vesicular exosome
Function catalytic activity, O-phospho-L-serine:2-oxoglutarate aminotransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (207)    Tissues (113)    Images (36)
Theiler Stages: 15, 19, 22, 23
Assay TypeResults
RNA in situ 207
cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000030919 (Evidence)
Ensembl Gene ModelENSMUSG00000024640 (Evidence)
Entrez Gene107272 (Evidence)
DFCITC1573903, TC1595550, TC1645985, TC1708595
DoTSDT.101394989, DT.101394991, DT.101394993, DT.102547171, DT.495237, DT.55258012, DT.97389703
NIA Mouse Gene IndexU038884
EC2.6.1.52
Consensus CDS ProjectCCDS29681.1, CCDS57139.1
International Mouse Knockout Project StatusPsat1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030919 VEGA Gene Model | MGI Sequence Detail 42660 C57BL/6J ±  kb
transcript OTTMUST00000076503 VEGA | MGI Sequence Detail 2617 Not Applicable 
polypeptide OTTMUSP00000040286 VEGA | MGI Sequence Detail 370 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(403 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000192 Aminotransferase, class V/Cysteine desulfurase
InterPro IPR020578 Aminotransferase class-V pyridoxal-phosphate binding site
InterPro IPR022278 Phosphoserine aminotransferase
InterPro IPR003248 Phosphoserine aminotransferase, subgroup
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Protein Ontology PR:000013339 phosphoserine aminotransferase
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:200082 White JK, et al., Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell. 2013 Jul 18;154(2):452-64
All references(41)
Other
accession IDs
MGI:1289292, MGI:2147628, MGI:2147656, MGI:3034454

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory