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Mcfd2
Gene Detail
 Symbol
Name
ID
Mcfd2
multiple coagulation factor deficiency 2
MGI:2183439
Synonyms 1810021C21Rik, F5F8D, LMAN1IP
Feature Type protein coding gene
Genetic Map
Chromosome 17
57.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:87254658-87265935 bp, - strand
From VEGA annotation of GRCm38

  11278 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44552  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mcfd2

Human
homologs
Human Homolog MCFD2, multiple coagulation factor deficiency 2
NCBI Gene ID 90411
neXtProt AC  NX_Q8NI22
Human Synonyms  F5F8D, F5F8D2, LMAN1IP, SDNSF
Human Chr (Location)  2p21; chr2:46901870-46941855 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MCFD2
Alleles
and
phenotypes
All alleles(9) : Targeted(2) Gene trapped(7)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process carboxylic acid metabolic process, protein transport, ...
Component endoplasmic reticulum, extracellular region, ...
Function calcium ion binding, metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (70)    Tissues (34)    Images (31)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 70
cDNA source data(146)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(147) cDNA(147)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000033021 (Evidence)
Ensembl Gene ModelENSMUSG00000024150 (Evidence)
Entrez Gene193813 (Evidence)
UniGene30251
DFCITC1572499
DoTSDT.102549257, DT.494195, DT.94273896, DT.94273897
NIA Mouse Gene IndexU038132
Consensus CDS ProjectCCDS29015.1
International Mouse Knockout Project StatusMcfd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033021 VEGA Gene Model | MGI Sequence Detail 11278 C57BL/6J ±  kb
transcript OTTMUST00000082388 VEGA | MGI Sequence Detail 1823 Not Applicable 
polypeptide OTTMUSP00000044152 VEGA | MGI Sequence Detail 145 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(8) UniProt(6)
Polymorphisms SNPs within 2kb(191 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000010239 multiple coagulation factor deficiency protein 2
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177067 Zhang B, et al., Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of {alpha}1-antitrypsin. Blood. 2011 Sep 22;118(12):3384-91
All references(38)
Other
accession IDs
MGI:1923602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory