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Cabp7 Gene Detail
Summary
  • Symbol
    Cabp7
  • Name
    calcium binding protein 7
  • Synonyms
    calneuron II
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183437
    NCBI Gene: 192650
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:4686892-4696778 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    257 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183437
 protein coding gene Chr11:4686892-4697179 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017988
 protein coding gene Chr11:1718813-1728748 (-)
A/J MGP_AJ_G0017961
 protein coding gene Chr11:1686978-1697969 (-)
AKR/J MGP_AKRJ_G0017925
 protein coding gene Chr11:1764366-1774274 (-)
BALB/cJ MGP_BALBcJ_G0017929
 protein coding gene Chr11:1662738-1672648 (-)
C3H/HeJ MGP_C3HHeJ_G0017742
 protein coding gene Chr11:1653627-1663513 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018381
 protein coding gene Chr11:1787862-1797748 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016039
 protein coding gene Chr11:1581245-1591407 (-)
CAST/EiJ MGP_CASTEiJ_G0017304
 protein coding gene Chr11:1628230-1643605 (-)
CBA/J MGP_CBAJ_G0017717
 protein coding gene Chr11:2060746-2070632 (-)
DBA/2J MGP_DBA2J_G0017827
 protein coding gene Chr11:1590631-1600517 (-)
FVB/NJ MGP_FVBNJ_G0017819
 protein coding gene Chr11:1628227-1638830 (-)
LP/J MGP_LPJ_G0017898
 protein coding gene Chr11:1811409-1821325 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017845
 protein coding gene Chr11:1728438-1739183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018421
 protein coding gene Chr11:1765811-1775709 (-)
PWK/PhJ MGP_PWKPhJ_G0017084
 protein coding gene Chr11:1597364-1609095 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016881
 protein coding gene Chr11:1736996-1746865 (-)
WSB/EiJ MGP_WSBEiJ_G0017358
 protein coding gene Chr11:1643372-1655391 (-)



Homology
more
  • Human Ortholog
    CABP7, calcium binding protein 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CABP7, calcium binding protein 7
  • Synonyms
    CALN2
  • Links
    NCBI Gene ID: 164633
    UniProt: Q86V35

  • Chr Location
    22q12.2; chr22:29720003-29731833 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for muscle-specific deletion exhibit accelerated age-related neuromuscular junction degeneration, muscle weakness/atrophy, and motor dysfunction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    2
  • cDNA Data
    5
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000009075 Ensembl Gene Model | MGI Sequence Detail 9887 C57BL/6J ±  kb
    transcript ENSMUST00000009219 Ensembl | MGI Sequence Detail 2628 Not Applicable  
    polypeptide ENSMUSP00000009219 Ensembl | MGI Sequence Detail 215 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 8
    • Earliest
      J:77561 Haeseleer F, et al., Calmodulin and Ca2+-binding proteins (CaBPs): variations on a theme. Adv Exp Med Biol. 2002;514:303-17
    • Latest
      J:345130 Eguchi T, et al., Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice. iScience. 2024 Feb 16;27(2):108997
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/24/2026
    MGI 6.24     		The Jackson Laboratory