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Med9 Gene Detail
Summary
  • Symbol
    Med9
  • Name
    mediator complex subunit 9
  • Synonyms
    Med25, MED25, MGC:30366
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183151
    NCBI Gene: 192191
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:59948206-59962205 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 37.81 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    94 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183151
protein coding gene Chr11:59948206-59963306 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018409
protein coding gene Chr11:59805266-59819260 (+)
A/J MGP_AJ_G0018378
protein coding gene Chr11:57533288-57545777 (+)
AKR/J MGP_AKRJ_G0018348
protein coding gene Chr11:59449361-59463496 (+)
BALB/cJ MGP_BALBcJ_G0018349
protein coding gene Chr11:57875424-57889403 (+)
C3H/HeJ MGP_C3HHeJ_G0018162
protein coding gene Chr11:59328351-59340840 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018801
protein coding gene Chr11:61704627-61720105 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016447
protein coding gene Chr11:54776614-54790866 (+)
CAST/EiJ MGP_CASTEiJ_G0017719
protein coding gene Chr11:59461149-59473412 (+)
CBA/J MGP_CBAJ_G0018136
protein coding gene Chr11:64406302-64418791 (+)
DBA/2J MGP_DBA2J_G0018245
protein coding gene Chr11:57189786-57203976 (+)
FVB/NJ MGP_FVBNJ_G0018236
protein coding gene Chr11:56849811-56863815 (+)
LP/J MGP_LPJ_G0018318
protein coding gene Chr11:60409024-60423025 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018260
protein coding gene Chr11:65484402-65498436 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018842
protein coding gene Chr11:59483160-59496926 (+)
PWK/PhJ MGP_PWKPhJ_G0017490
protein coding gene Chr11:57790853-57803370 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017282
protein coding gene Chr11:59274666-59291130 (+)
WSB/EiJ MGP_WSBEiJ_G0017770
protein coding gene Chr11:59154445-59168444 (+)



Homology
more
  • Human Ortholog
    MED9, mediator complex subunit 9
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MED9, mediator complex subunit 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MED25
  • Links
    NCBI Gene ID: 55090
    neXtProt AC: NX_Q9NWA0
    UniProt: Q9NWA0

  • Chr Location
    17p11.2; chr17:17476986-17493220 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32385
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MED9
  • Gene Tree
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061650 Ensembl Gene Model | MGI Sequence Detail 14000 C57BL/6J ±  kb
transcript ENSMUST00000081980 Ensembl | MGI Sequence Detail 1920 Not Applicable  
polypeptide ENSMUSP00000080641 Ensembl | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010308 mediator of RNA polymerase II transcription subunit 9
  • InterPro Domains
    IPR037212 Mediator complex, subunit Med7/Med21-like
    IPR011425 Mediator of RNA polymerase II transcription subunit 9
    IPR039242 Mediator of RNA polymerase II transcription subunit 9, metazoan
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Diseases 3
    Gene Ontology 5
    Phenotypes 18
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:185284 Lacaria M, et al., Enriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits. Hum Mol Genet. 2012 Jul 15;21(14):3083-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory