About   Help   FAQ
Sardh
Gene Detail
 Symbol
Name
ID
Sardh
sarcosine dehydrogenase
MGI:2183102
Synonyms MGC:6279
Feature Type protein coding gene
Genetic Map
Chromosome 2
19.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:27188393-27248337 bp, - strand
From VEGA annotation of GRCm38

  59945 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sardh

Human
homologs
Human Homolog SARDH, sarcosine dehydrogenase
NCBI Gene ID 1757
neXtProt AC  NX_Q9UL12
Human Synonyms  BPR-2, DMGDHL1, SAR, SARD, SDH
Human Chr (Location)  9q33-q34; chr9:133663560-133739955 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SARDH
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process glycine catabolic process, oxidation-reduction process, ...
Component cytoplasm, mitochondrial matrix, ...
Function aminomethyltransferase activity, flavin adenine dinucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(152)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(153) cDNA(152) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000012037 (Evidence)
Ensembl Gene ModelENSMUSG00000009614 (Evidence)
Entrez Gene192166 (Evidence)
UniGene278467
DFCITC1575190, TC1579917, TC1694843
DoTSDT.110654709, DT.493914, DT.55129459
NIA Mouse Gene IndexU022441
EC1.5.8.3
Consensus CDS ProjectCCDS15826.1
International Mouse Knockout Project StatusSardh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012037 VEGA Gene Model | MGI Sequence Detail 59945 C57BL/6J ±  kb
transcript OTTMUST00000028625 VEGA | MGI Sequence Detail 4521 Not Applicable 
polypeptide OTTMUSP00000012947 VEGA | MGI Sequence Detail 919 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(469 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006076 FAD dependent oxidoreductase
InterPro IPR013977 Glycine cleavage T-protein, C-terminal barrel
InterPro IPR006222 Glycine cleavage T-protein, N-terminal
InterPro IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1
Protein Ontology PR:000014456 sarcosine dehydrogenase, mitochondrial
References (Earliest) J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory