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Sardh
Gene Detail
Symbol

Name
ID
Sardh
sarcosine dehydrogenase
MGI:2183102
Synonyms
MGC:6279
Feature Type
protein coding gene
Genetic Map
Chromosome 2
19.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:27188393-27248337 bp, - strand
From VEGA annotation of GRCm38

  59945 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SARDH
Gene Tree: Sardh

Human
homologs
SARDH, sarcosine dehydrogenase
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1757
neXtProt AC: NX_Q9UL12

Human Synonyms: BPR-2, DMGDHL1, SAR, SARD, SDH

Human Chr (Location): 9q33-q34; chr9:133661740-133739955 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SARDH

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sardh interacts with 166 markers (Mir27a, Mir27b, Mir29a, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(152)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sardh ; ZFIN sardh    NEW 
Molecular
reagents
All nucleic(153) cDNA(152) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000012037 (Evidence)
Ensembl Gene Model ENSMUSG00000009614 (Evidence)
Entrez Gene 192166 (Evidence)
UniGene 278467
DFCI TC1694843, TC1579917, TC1575190
DoTS DT.493914, DT.55129459, DT.110654709
NIA Mouse Gene Index U022441
EC 1.5.8.3
Consensus CDS Project CCDS15826.1
International Mouse Phenotyping Consortium Status Sardh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012037 VEGA Gene Model | MGI Sequence Detail 59945 C57BL/6J ±  kb
transcript OTTMUST00000028625 VEGA | MGI Sequence Detail 4521 Not Applicable 
polypeptide OTTMUSP00000012947 VEGA | MGI Sequence Detail 919 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(469 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006076 FAD dependent oxidoreductase
InterPro IPR013977 Glycine cleavage T-protein, C-terminal barrel
InterPro IPR006222 Glycine cleavage T-protein, N-terminal
InterPro IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1
Protein Ontology PR:000014456 sarcosine dehydrogenase, mitochondrial
References
(Earliest) J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory