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Kat7
Gene Detail
Symbol

Name
ID
Kat7
K(lysine) acetyltransferase 7
MGI:2182799
Synonyms
Hbo1, Hboa, MGC:56758, Myst2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
59.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:95274259-95310246 bp, - strand
From VEGA annotation of GRCm38

  35988 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5134  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Kat7

Human
homologs
Human Homolog KAT7, K(lysine) acetyltransferase 7
NCBI Gene ID 11143
neXtProt AC  NX_O95251
Human Synonyms  HBO1, HBOA, MYST2, ZC2HC7
Human Chr (Location)  17q21.32; chr17:49788619-49829096 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(173) : Gene trapped(170) Targeted(3)
Genomic Mutations involving Kat7 (1)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit embryonic growth arrest, incomplete embryo turning, disorganized yolk sac vascular plexus, and increased apoptosis.
 
Interactions
Kat7 interacts with 299 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process chromatin modification, DNA replication, ...
Component cytoplasm, histone acetyltransferase complex, ...
Function histone acetyltransferase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (40)    Tissues (39)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 32
RT-PCR 8
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001619 (Evidence)
Ensembl Gene ModelENSMUSG00000038909 (Evidence)
Entrez Gene217127 (Evidence)
DFCITC1595002, TC1573201, TC1598263, TC1667215
DoTSDT.110523076, DT.101137976, DT.101317788, DT.97385011, DT.97345468, DT.91566590, DT.40165383, DT.493269
NIA Mouse Gene IndexU033300
EC2.3.1.48
Consensus CDS ProjectCCDS25275.1, CCDS56798.1, CCDS56799.1
International Mouse Knockout Project StatusKat7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001619 VEGA Gene Model | MGI Sequence Detail 35988 C57BL/6J ±  kb
transcript OTTMUST00000003170 VEGA | MGI Sequence Detail 3414 Not Applicable 
polypeptide OTTMUSP00000001535 VEGA | MGI Sequence Detail 613 Not Applicable 

For the selected sequences
All sequences(120) RefSeq(20) UniProt(11)
Polymorphisms
SNPs within 2kb(317 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016181 Acyl-CoA N-acyltransferase
InterPro IPR002717 MOZ/SAS-like protein
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR002515 Zinc finger, C2HC-type
Protein Ontology PR:000010889 histone acetyltransferase KAT7
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory