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Adgrf2 Gene Detail
Summary
  • Symbol
    Adgrf2
  • Name
    adhesion G protein-coupled receptor F2
  • Synonyms
    Gpr111, PGR20
  • Feature Type
    protein coding gene
  • IDs
    MGI:2182728
    NCBI Gene: 435529
  • Gene Overview
    MyGene.info: ADGRF2
Location & Maps
more
  • Sequence Map
    Chr17:42708936-42742179 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33244 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.66 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ADGRF2, adhesion G protein-coupled receptor F2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ADGRF2, adhesion G protein-coupled receptor F2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GPR111, hGPCR35, PGR20
  • Links
    NCBI Gene ID: 222611
    neXtProt AC: NX_Q8IZF7

  • Chr Location
    6p12.3; chr6:47656590-47697797 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotype references
Mice homozygous for a reporter allele exhibit normal viability and fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032803 VEGA Gene Model | MGI Sequence Detail 33244 C57BL/6J ±  kb
transcript OTTMUST00000081700 VEGA | MGI Sequence Detail 3284 Not Applicable  
polypeptide OTTMUSP00000043737 VEGA | MGI Sequence Detail 644 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    578 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031052 adhesion G-protein coupled receptor F2
  • InterPro Domains
    IPR008078 GPCR family 2, Ig-hepta-like receptor
    IPR017981 GPCR, family 2-like
    IPR000832 GPCR, family 2, secretin-like
    IPR000203 GPS motif
Molecular
Reagents
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  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:90622 Bjarnadottir TK, et al., The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics. 2004 Jul;84(1):23-33
  • Latest
    J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory