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Acsf3 Gene Detail
Summary
  • Symbol
    Acsf3
  • Name
    acyl-CoA synthetase family member 3
  • Synonyms
    MGC:37904
  • Feature Type
    protein coding gene
  • IDs
    MGI:2182591
    NCBI Gene: 257633
  • Gene Overview
    MyGene.info: ACSF3
Location & Maps
more
  • Sequence Map
    Chr8:122775505-122817880 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42376 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 71.97 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ACSF3, acyl-CoA synthetase family member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ACSF3, acyl-CoA synthetase family member 3
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 197322
    neXtProt AC: NX_Q4G176

  • Chr Location
    16q24.3; chr16:89093809-89155846 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ACSF3 associations

Human Disease Mouse Models
       Combined Malonic and Methylmalonic Aciduria; CMAMMA   OMIM: 614265
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015016 Ensembl Gene Model | MGI Sequence Detail 42376 C57BL/6J ±  kb
transcript ENSMUST00000015160 Ensembl | MGI Sequence Detail 2206 Not Applicable  
polypeptide ENSMUSP00000015160 Ensembl | MGI Sequence Detail 583 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    307 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000003658 acyl-CoA synthetase family member 3, mitochondrial
  • EC
  • InterPro Domains
    IPR020845 AMP-binding, conserved site
    IPR025110 AMP-binding enzyme C-terminal domain
    IPR000873 AMP-dependent synthetase/ligase
Molecular
Reagents
less
  • All nucleic 42
    cDNA 41
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144599
References
more
  • Summaries
    All 24
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory