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Ddx50 Gene Detail
Summary
  • Symbol
    Ddx50
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • Synonyms
    4933429B04Rik, 8430408E17Rik, GU2, RH-II/Gubeta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2182303
    NCBI Gene: 94213
  • Gene Overview
    MyGene.info: DDX50
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:62615895-62651218 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    63 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2182303
protein coding gene Chr10:62615895-62651603 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017303
protein coding gene Chr10:62058963-62097116 (-)
A/J MGP_AJ_G0017281
protein coding gene Chr10:60157325-60192596 (-)
AKR/J MGP_AKRJ_G0017241
protein coding gene Chr10:61721401-61759082 (-)
BALB/cJ MGP_BALBcJ_G0017241
protein coding gene Chr10:60241152-60276490 (-)
C3H/HeJ MGP_C3HHeJ_G0017064
protein coding gene Chr10:61641840-61681621 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017699
protein coding gene Chr10:64269415-64316280 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015389
protein coding gene Chr10:57124785-57156330 (-)
CAST/EiJ MGP_CASTEiJ_G0016635
protein coding gene Chr10:61698320-61733854 (-)
CBA/J MGP_CBAJ_G0017036
protein coding gene Chr10:66687962-66732918 (-)
DBA/2J MGP_DBA2J_G0017141
protein coding gene Chr10:59428693-59466436 (-)
FVB/NJ MGP_FVBNJ_G0017135
protein coding gene Chr10:58698537-58732149 (-)
LP/J MGP_LPJ_G0017215
protein coding gene Chr10:62442530-62492647 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017163
protein coding gene Chr10:68901837-68944994 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017737
protein coding gene Chr10:61567201-61605366 (-)
PWK/PhJ MGP_PWKPhJ_G0016418
protein coding gene Chr10:59302331-59337480 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016200
protein coding gene Chr10:60928012-60967079 (-)
WSB/EiJ MGP_WSBEiJ_G0016699
protein coding gene Chr10:61504158-61543362 (-)



Homology
more
  • Human Ortholog
    DDX50, DExD-box helicase 50
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DDX50, DExD-box helicase 50
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GU2, GUB, mcdrh, RH-II/GuB
  • Links
    NCBI Gene ID: 79009
    neXtProt AC: NX_Q9BQ39
    UniProt: Q9BQ39

  • Chr Location
    10q22.1; chr10:68901278-68956312 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020076 Ensembl Gene Model | MGI Sequence Detail 35324 C57BL/6J ±  kb
transcript ENSMUST00000020270 Ensembl | MGI Sequence Detail 2535 Not Applicable  
polypeptide ENSMUSP00000020270 Ensembl | MGI Sequence Detail 734 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:1918714, MGI:2444944
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory