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Clca4
Gene Detail
 Symbol
Name
ID
Clca4
chloride channel calcium activated 4
MGI:2181989
Feature Type protein coding gene
Genetic Map
Chromosome 3
69.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:144822623-144849357 bp, - strand
From VEGA annotation of GRCm38

  26735 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135610  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: calcium-activated chloride channel
Gene Tree: Clca4

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Clca4 interacts with 40 markers (Mir16-1, Mir32, Mir33, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (84)    Tissues (35)    Images (26)
Theiler Stages: 21, 23, 25, 27, 28
Assay TypeResults
RNA in situ 59
RT-PCR 25
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(13) Primer pair(4) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000030497 (Evidence)
Ensembl Gene ModelENSMUSG00000037033 (Evidence)
Entrez Gene229927 (Evidence)
UniGene290600
DFCITC1589381, TC1605539
DoTSDT.101357271, DT.91436193
NIA Mouse Gene IndexU136123
Consensus CDS ProjectCCDS51086.1
International Mouse Knockout Project StatusClca4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030497 VEGA Gene Model | MGI Sequence Detail 26735 C57BL/6J ±  kb
transcript OTTMUST00000075517 VEGA | MGI Sequence Detail 3361 Not Applicable 
polypeptide OTTMUSP00000039602 VEGA | MGI Sequence Detail 1044 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)    SNPs within 2kb including multiple locations(84)
Protein-related
information
ResourceIDDescription
InterPro IPR004727 Calcium-activated chloride channel protein
InterPro IPR013642 Chloride channel calcium-activated
InterPro IPR015394 Domain of unknown function DUF1973
InterPro IPR003961 Fibronectin, type III
InterPro IPR002035 von Willebrand factor, type A
References (Earliest) J:76835 Elble RC, et al., Molecular and functional characterization of a murine calcium-activated chloride channel expressed in smooth muscle. J Biol Chem. 2002 May 24;277(21):18586-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory