Clca4
Gene Detail

Symbol Name ID

Clca4 chloride channel calcium activated 4 MGI:2181989

Feature Type

protein coding gene

Genetic Map

Chromosome 3

69.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:144822623-144849357 bp, - strand From VEGA annotation of GRCm38   26735 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:77224  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 2 cattle; 1 dog; 1 chicken

Protein SuperFamily: calcium-activated chloride channel
Gene Tree: Clca4

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	biological_process
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (84)    Tissues (33)    Images (26)
Theiler Stages: 21, 23, 25, 28

Assay Type	Results
RNA in situ	59
RT-PCR	25

cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) cDNA(13) Primer pair(4) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000030497 (Evidence)
Ensembl Gene Model	ENSMUSG00000037033 (Evidence)
Entrez Gene	229927 (Evidence)
UniGene	290600
DFCI	TC1589381, TC1605539
DoTS	DT.101357271, DT.91436193
NIA Mouse Gene Index	U136123
Consensus CDS Project	CCDS51086.1
International Mouse Knockout Project Status	Clca4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030497	VEGA Gene Model | MGI Sequence Detail	26735	C57BL/6J
transcript	OTTMUST00000075517	VEGA | MGI Sequence Detail	3361	Not Applicable
polypeptide	OTTMUSP00000039602	VEGA | MGI Sequence Detail	1044	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(67 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004727	Calcium-activated chloride channel protein
InterPro	IPR013642	Chloride channel calcium-activated
InterPro	IPR015394	Domain of unknown function DUF1973
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR002035	von Willebrand factor, type A

References

(Earliest) J:76835 Elble RC, et al., Molecular and functional characterization of a murine calcium-activated chloride channel expressed in smooth muscle. J Biol Chem. 2002 May 24;277(21):18586-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)