Xrra1 Gene Detail

Summary

• Symbol
  Xrra1
• Name
  X-ray radiation resistance associated 1

• Feature Type
  protein coding gene
• IDs
  MGI:2181647
  NCBI Gene: 446101

Location & Maps

• Sequence Map
  Chr7:99859116-99917822 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    58707 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 54.15 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  XRRA1, X-ray radiation resistance associated 1

• Vertebrate Orthologs
  9

• Human Ortholog
  XRRA1, X-ray radiation resistance associated 1
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:18868

  NCBI Gene ID: 143570

  neXtProt AC: NX_Q6P2D8

  UniProt: Q6P2D8

  
  
• Chr Location
  11q13.4; chr11:74840910-74949187 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 19547
  1 human;1 mouse;1 rat;1 chimpanzee;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: XRRA1
• Gene Tree
  Xrra1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Xrra1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  15 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  5
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  5

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Xrra1 interacts with 44 markers (Mir26b, Mir32, Mir92-1, ...) View All

Sequences &
Gene Models

• All Sequences
  35
• RefSeq
  8
• UniProt
  3
• CCDS
  CCDS52321.1

• VEGA
  OTTMUSG00000059072 (Evidence)
• Ensembl
  ENSMUSG00000035211 (Evidence)
• NCBI Gene
  446101

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000059072	VEGA Gene Model | MGI Sequence Detail	58707	C57BL/6J
transcript	OTTMUST00000144908	VEGA | MGI Sequence Detail	2731	Not Applicable
polypeptide	OTTMUSP00000075502	VEGA | MGI Sequence Detail	786	Not Applicable

Polymorphisms

• SNPs within 2kb
  576 from dbSNP Build 142

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000017513 X-ray radiation resistance-associated protein 1
  (term hierarchy)
• InterPro Domains
  IPR001611 Leucine-rich repeat
  IPR032675 Leucine-rich repeat domain, L domain-like
  IPR003591 Leucine-rich repeat, typical subtype

Molecular
Reagents

• All nucleic 5

  cDNA 5

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:2141964

References

• Summaries
  All 28

  Gene Ontology 1

  Phenotypes 10
• Earliest
  J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582