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Ripply3
Gene Detail
 Symbol
Name
ID
Ripply3
ripply3 homolog (zebrafish)
MGI:2181192
Synonyms Dscr6
Feature Type protein coding gene
Genetic Map
Chromosome 16
55.17 cM, cytoband C4
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:94328420-94336935 bp, + strand
From VEGA annotation of GRCm38

  8516 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10350  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Ripply3

Human
homologs
Human Homolog RIPPLY3, ripply transcriptional repressor 3
NCBI Gene ID 53820
neXtProt AC  NX_P57055
Human Synonyms  DSCR6
Human Chr (Location)  21q22.2; chr21:37006156-37019659 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Ripply3 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a reporter allele show complete neonatal lethality, abnormal development of the pharyngeal apparatus and its derivatives including ectopic formation of the thymus and the parathyroid gland, and cardiovascular defects such as deletion of the aortic arch and misshapen great vessels.
 
Interactions
Ripply3 interacts with 153 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process heart development, multicellular organismal development, ...
Component nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (63)    Tissues (63)    Images (2)
Theiler Stages: 13, 15, 17, 20, 22, 26, 28
Assay TypeResults
RNA in situ 47
RT-PCR 16
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000019884 (Evidence)
Ensembl Gene ModelENSMUSG00000022941 (Evidence)
Entrez Gene170765 (Evidence)
UniGene42604
DFCITC1584917
DoTSDT.91411473
NIA Mouse Gene IndexU017409
Consensus CDS ProjectCCDS28347.1
International Mouse Knockout Project StatusRipply3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019884 VEGA Gene Model | MGI Sequence Detail 8516 C57BL/6J ±  kb
transcript OTTMUST00000047411 VEGA | MGI Sequence Detail 1531 Not Applicable 
polypeptide OTTMUSP00000021423 VEGA | MGI Sequence Detail 152 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006701 protein ripply3
References (Earliest) J:80502 Reymond A, et al., Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory