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Rfxap Gene Detail
Summary
  • Symbol
    Rfxap
  • Name
    regulatory factor X-associated protein
  • Synonyms
    5730495K23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2180854
    NCBI Gene: 170767
  • Gene Overview
    MyGene.info: RFXAP
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:54803115-54807791 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 25.69 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2180854
protein coding gene Chr3:54803115-54807791 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027217
protein coding gene Chr3:53514012-53518688 (-)
A/J MGP_AJ_G0027177
protein coding gene Chr3:51861295-51865971 (-)
AKR/J MGP_AKRJ_G0027147
protein coding gene Chr3:52930263-52934939 (-)
BALB/cJ MGP_BALBcJ_G0027190
protein coding gene Chr3:51714675-51719351 (-)
C3H/HeJ MGP_C3HHeJ_G0026933
protein coding gene Chr3:53137153-53141829 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027636
protein coding gene Chr3:55554666-55559342 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024995
protein coding gene Chr3:48381787-48386636 (-)
CAST/EiJ MGP_CASTEiJ_G0026385
protein coding gene Chr3:53275623-53280181 (-)
CBA/J MGP_CBAJ_G0026909
protein coding gene Chr3:57333703-57338379 (-)
DBA/2J MGP_DBA2J_G0027043
protein coding gene Chr3:51419035-51423711 (-)
FVB/NJ MGP_FVBNJ_G0027011
protein coding gene Chr3:50396377-50401053 (-)
LP/J MGP_LPJ_G0027155
protein coding gene Chr3:54223364-54228129 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027029
protein coding gene Chr3:61432071-61436747 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027694
protein coding gene Chr3:52841961-52846637 (-)
PWK/PhJ MGP_PWKPhJ_G0026117
protein coding gene Chr3:51096228-51100891 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025930
protein coding gene Chr3:52599742-52603386 (-)
WSB/EiJ MGP_WSBEiJ_G0026459
protein coding gene Chr3:52975783-52980444 (-)



Homology
more
  • Human Ortholog
    RFXAP, regulatory factor X associated protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RFXAP, regulatory factor X associated protein
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 5994
    neXtProt AC: NX_O00287
    UniProt: O00287

  • Chr Location
    13q13.3; chr13:36819202-36829603 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human RFXAP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 170767 NCBI Gene Model | MGI Sequence Detail 4677 C57BL/6J ±  kb
transcript NM_133231 RefSeq | MGI Sequence Detail 2185 C57BL/6  
polypeptide Q8VCG9 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR029316 Regulatory factor X-associated protein, RFXANK-binding domain
    IPR038308 RFXAP, C-terminal domain superfamily
Molecular
Reagents
less
  • All nucleic 36
    cDNA 35
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444693
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory