Oasl1
Gene Detail

Symbol Name ID

Oasl1 2'-5' oligoadenylate synthetase-like 1 MGI:2180849

Synonyms

7530414C13Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

55.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:114923240-114937915 bp, + strand From VEGA annotation of GRCm38   14676 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Oasl1

Human homologs

Human Homolog		OASL, 2'-5'-oligoadenylate synthetase-like
NCBI Gene ID		8638
neXtProt AC		NX_Q15646
Human Synonyms		OASLd, p59OASL, p59 OASL, p59-OASL, TRIP14, TRIP-14
Human Chr (Location)		12q24.2; chr12:121458095-121477045 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	defense response to virus, immune response, ...
Component	cytoplasm, nucleolus, ...
Function	ATP binding, DNA binding, ...

External Resources: FuncBase

Expression

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) cDNA(25)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000014607 (Evidence)
Ensembl Gene Model	ENSMUSG00000041827 (Evidence)
Entrez Gene	231655 (Evidence)
UniGene	95479
DFCI	TC1572588
DoTS	DT.101360049, DT.94028763, DT.99857563
NIA Mouse Gene Index	U006039
Consensus CDS Project	CCDS19575.1
International Mouse Knockout Project Status	Oasl1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014607	VEGA Gene Model | MGI Sequence Detail	14676	C57BL/6J
transcript	OTTMUST00000034645	VEGA | MGI Sequence Detail	2125	Not Applicable
polypeptide	OTTMUSP00000015517	VEGA | MGI Sequence Detail	511	Not Applicable

All sequences(40) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(43 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026774	2'-5'-oligoadenylate synthase
InterPro	IPR018952	2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro	IPR006117	2-5-oligoadenylate synthetase, conserved site
InterPro	IPR006116	2-5-oligoadenylate synthetase, N-terminal
InterPro	IPR000626	Ubiquitin
InterPro	IPR019955	Ubiquitin supergroup
Protein Ontology	PR:000034502	2'-5'-oligoadenylate synthase-like protein 1

References

(Earliest) J:77001 Perelygin AA, et al., Positional cloning of the murine flavivirus resistance gene. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9322-7
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(31)

Other accession IDs

MGI:2443464