About   Help   FAQ
Neto1
Gene Detail
Symbol

Name
ID
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
MGI:2180216
Synonyms
C130005O10Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 18
58.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:86394952-86501897 bp, + strand
From NCBI annotation of GRCm38

  106946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16367  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Neto1

Human
homologs
Human Homolog NETO1, neuropilin (NRP) and tolloid (TLL)-like 1
NCBI Gene ID 81832
neXtProt AC  NX_Q8TDF5
Human Synonyms  BCTL1, BTCL1
Human Chr (Location)  18q22.2; chr18:72742314-72867591 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit depressed long term potentiation, reduced NMDAR excitatory postsynaptic potentiation, and decreased spartial learning and working memory.
 
Interactions
Neto1 interacts with 285 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000050321 (Evidence)
Entrez Gene246317 (Evidence)
DFCITC1585652, TC1597758, TC1697011
DoTSDT.110774034, DT.87047705
NIA Mouse Gene IndexU018976
Consensus CDS ProjectCCDS29387.1
International Mouse Knockout Project StatusNeto1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 246317 NCBI Gene Model | MGI Sequence Detail 106946 C57BL/6J ±  kb
transcript NM_144946 RefSeq | MGI Sequence Detail 3531 C57BL/6 
polypeptide Q8R4I7 UniProt | EBI | MGI Sequence Detail 533 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(18) UniProt(1)
Polymorphisms
SNPs within 2kb(834 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000859 CUB domain
InterPro IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
InterPro IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Protein Ontology PR:000011143 neuropilin and tolloid-like protein 1
Graphical View of Protein Domain Structure
References
(Earliest) J:76401 Stohr H, et al., A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain. Gene. 2002 Mar 20;286(2):223-31
(Latest) J:205577 Wyeth MS, et al., Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses. J Neurosci. 2014 Jan 8;34(2):622-8
All references(34)
Other
accession IDs
MGI:2147275, MGI:2443543

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory