About   Help   FAQ
Neto1
Gene Detail
Symbol

Name
ID
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
MGI:2180216
Synonyms
C130005O10Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 18
58.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:86394952-86501897 bp, + strand
From Ensembl annotation of GRCm38

  106946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16367  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NETO1
Gene Tree: Neto1

Human
homologs
NETO1, neuropilin (NRP) and tolloid (TLL)-like 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 81832
neXtProt AC: NX_Q8TDF5

Human Synonyms: BCTL1, BTCL1

Human Chr (Location): 18q22.2; chr18:72742314-72867575 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit depressed long term potentiation, reduced NMDAR excitatory postsynaptic potentiation, and decreased spartial learning and working memory.
 
Interactions
Neto1 interacts with 285 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase neto1    NEW 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000050321 (Evidence)
Entrez Gene 246317 (Evidence)
DFCI TC1697011, TC1597758, TC1585652
DoTS DT.110774034, DT.87047705
NIA Mouse Gene Index U018976
Consensus CDS Project CCDS29387.1
International Mouse Phenotyping Consortium Status Neto1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050321 Ensembl Gene Model | MGI Sequence Detail 106946 C57BL/6J ±  kb
transcript ENSMUST00000058829 Ensembl | MGI Sequence Detail 3531 Not Applicable 
polypeptide ENSMUSP00000057340 Ensembl | MGI Sequence Detail 533 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(20) UniProt(1)
Polymorphisms
SNPs within 2kb(834 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000859 CUB domain
InterPro IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
InterPro IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Protein Ontology PR:000011143 neuropilin and tolloid-like protein 1
References
(Earliest) J:76401 Stohr H, et al., A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain. Gene. 2002 Mar 20;286(2):223-31
(Latest) J:205577 Wyeth MS, et al., Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses. J Neurosci. 2014 Jan 8;34(2):622-8
All references(33)
Other
accession IDs
MGI:2147275, MGI:2443543

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory