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Oxr1
Gene Detail
Symbol

Name
ID
Oxr1
oxidation resistance 1
MGI:2179326
Synonyms
2210416C20Rik, C7, C7B
Feature Type
protein coding gene
Genetic Map
Chromosome 15
16.06 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:41447482-41861048 bp, + strand
From NCBI annotation of GRCm38

  413567 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:24993  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Oxr1

Human
homologs
Human Homolog OXR1, oxidation resistance 1
NCBI Gene ID 55074
neXtProt AC  NX_Q8N573
Human Synonyms  TLDC3
Human Chr (Location)  8q23; chr8:106270178-106752694 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(71) : Gene trapped(66) Spontaneous(1) Targeted(4)
Genomic Mutations involving Oxr1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene-trap allele exhibit no abnormal phenotype.
 
Interactions
Oxr1 interacts with 333 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process adult walking behavior, cellular response to hydroperoxide, ...
Component mitochondrion, nucleolus, ...
Function oxidoreductase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 10
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(5)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170719 NCBI Gene Model | MGI Sequence Detail 413567 C57BL/6J ±  kb
transcript NM_001130166 RefSeq | MGI Sequence Detail 4616 C57BL/6 
polypeptide Q4KMM3 UniProt | EBI | MGI Sequence Detail 866 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(26) UniProt(7)
Polymorphisms
SNPs within 2kb(4117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018392 Peptidoglycan-binding lysin domain
InterPro IPR006571 TLDc
Protein Ontology PR:000012097 oxidation resistance protein 1
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177995 Oliver PL, et al., Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration. PLoS Genet. 2011 Sep;7(10):e1002338
All references(36)
Other
accession IDs
MGI:1922080

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory