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Oxr1 Gene Detail
Summary
  • Symbol
    Oxr1
  • Name
    oxidation resistance 1
  • Synonyms
    2210416C20Rik, C7, C7B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179326
    NCBI Gene: 170719
  • Gene Overview
    MyGene.info: OXR1
Location & Maps
more
  • Sequence Map
    Chr15:41447482-41861048 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      413567 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 16.06 cM, cytoband D1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    OXR1, oxidation resistance 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    OXR1, oxidation resistance 1
    Orthology source: HomoloGene
  • Synonyms
    Nbla00307, TLDC3
  • Links
    NCBI Gene ID: 55074
    neXtProt AC: NX_Q8N573

  • Chr Location
    8q23; chr8:106270178-106752694 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 24993
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: OXR1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    74
  • Chemically induced (other)
    2
  • Gene trapped
    66
  • Spontaneous
    1
  • Targeted
    4
  • Transgenic
    1
  • Genomic Mutations
    3 involving Oxr1
  • Incidental Mutations
Mice homozygous for a gene-trap allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 170719 NCBI Gene Model | MGI Sequence Detail 413567 C57BL/6J ±  kb
transcript NM_001130166 RefSeq | MGI Sequence Detail 4616 C57BL/6  
polypeptide Q4KMM3 UniProt | EBI | MGI Sequence Detail 866 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    4075 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:1922080
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:230923 Finelli MJ, et al., The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against Oxidative Stress. J Biol Chem. 2016 Feb 5;291(6):2751-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory