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Oxr1
Gene Detail
 Symbol
Name
ID
Oxr1
oxidation resistance 1
MGI:2179326
Synonyms 2210416C20Rik, C7, C7B
Feature Type protein coding gene
Genetic Map
Chromosome 15
16.06 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:41447482-41861048 bp, + strand
From NCBI annotation of GRCm38

  413567 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:24993  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Oxr1

Human
homologs
Human Homolog OXR1, oxidation resistance 1
NCBI Gene ID 55074
neXtProt AC  NX_Q8N573
Human Synonyms  TLDC3
Human Chr (Location)  8q23; chr8:106270178-106752694 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(71) : Gene trapped(66) Spontaneous(1) Targeted(4)
Genomic Mutations involving Oxr1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene-trap allele exhibit no abnormal phenotype.
 
Interactions
Oxr1 interacts with 333 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process adult walking behavior, cellular response to hydroperoxide, ...
Component mitochondrion, nucleolus, ...
Function oxidoreductase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (6)   
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
Northern blot 10
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000022307 (Evidence)
Entrez Gene170719 (Evidence)
DFCITC1576174, TC1596940, TC1642614, TC1653902, TC1660650, TC1703277
DoTSDT.101408210, DT.110829777, DT.60101607, DT.91298743, DT.91305483, DT.94215992, DT.97389845, DT.99853991
Consensus CDS ProjectCCDS27448.1, CCDS49598.1, CCDS49599.1, CCDS49600.1, CCDS49601.1
International Mouse Knockout Project StatusOxr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170719 NCBI Gene Model | MGI Sequence Detail 413567 C57BL/6J ±  kb
transcript NM_001130166 RefSeq | MGI Sequence Detail 4616 C57BL/6 
polypeptide Q4KMM3 UniProt | EBI | MGI Sequence Detail 866 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(26) UniProt(4)
Polymorphisms SNPs within 2kb(4117 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018392 Peptidoglycan-binding lysin domain
InterPro IPR006571 TLDc
Protein Ontology PR:000012097 oxidation resistance protein 1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177995 Oliver PL, et al., Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration. PLoS Genet. 2011 Sep;7(10):e1002338
All references(36)
Other
accession IDs
MGI:1922080

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory