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Rttn
Gene Detail
 Symbol
Name
ID
Rttn
rotatin
MGI:2179288
Synonyms 4921538A15Rik, C530033I08Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
58.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:88971790-89131013 bp, + strand
From Ensembl annotation of GRCm38

  159224 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:65275  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rttn

Human
homologs
Human Homolog RTTN, rotatin
NCBI Gene ID 25914
neXtProt AC  NX_Q86VV8
Human Chr (Location)  18q22.2; chr18:70003804-70205726 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RTTN
Alleles
and
phenotypes
All alleles(15) : Gene trapped(12) Targeted(2) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an insertional mutation exhibit embryonic lethality and neurulation defects resulting in the arrest of gastrulation movements and abnormal left-right specification in the heart.
 
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process determination of left/right symmetry, multicellular organismal development
Component cell projection, ciliary basal body, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (1)   
Theiler Stages: 15
Assay TypeResults
RT-PCR 2
cDNA source data(30)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(31) cDNA(30) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000023066 (Evidence)
Entrez Gene246102 (Evidence)
UniGene772
DFCITC1584947, TC1589865, TC1593363, TC1597569, TC1600586, TC1747426
DoTSDT.101364242, DT.110784464, DT.91373198, DT.94174428, DT.99849738, DT.99856069
NIA Mouse Gene IndexU043694
Consensus CDS ProjectCCDS29390.1
International Mouse Knockout Project StatusRttn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023066 Ensembl Gene Model | MGI Sequence Detail 159224 C57BL/6J ±  kb
transcript ENSMUST00000023828 Ensembl | MGI Sequence Detail 7268 Not Applicable 
polypeptide ENSMUSP00000023828 Ensembl | MGI Sequence Detail 2226 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(448 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000014357 rotatin
References (Earliest) J:47980 Stoykova A, et al., Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system. Dev Dyn. 1998 Jun;212(2):198-213
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:1918209, MGI:2147258, MGI:2441910

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory