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Rtn4ip1 Gene Detail
Summary
  • Symbol
    Rtn4ip1
  • Name
    reticulon 4 interacting protein 1
  • Synonyms
    D10Ertd690e, NIMP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2178759
    NCBI Gene: 170728
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:43901714-43947864 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 23.12 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2178759
protein coding gene Chr10:43901714-43957201 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017198
protein coding gene Chr10:42690014-42736075 (+)
A/J MGP_AJ_G0017176
protein coding gene Chr10:41502629-41549090 (+)
AKR/J MGP_AKRJ_G0017136
protein coding gene Chr10:42132308-42178702 (+)
BALB/cJ MGP_BALBcJ_G0017137
protein coding gene Chr10:41541795-41587812 (+)
C3H/HeJ MGP_C3HHeJ_G0016958
protein coding gene Chr10:42483815-42530266 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017597
protein coding gene Chr10:44022417-44068759 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015292
protein coding gene Chr10:39434124-39483324 (+)
CAST/EiJ MGP_CASTEiJ_G0016537
protein coding gene Chr10:42718236-42767595 (+)
CBA/J MGP_CBAJ_G0016932
protein coding gene Chr10:46013184-46059243 (+)
DBA/2J MGP_DBA2J_G0017038
protein coding gene Chr10:40954578-41000637 (+)
FVB/NJ MGP_FVBNJ_G0017033
protein coding gene Chr10:40447248-40493307 (+)
LP/J MGP_LPJ_G0017114
protein coding gene Chr10:42730664-42777451 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017062
protein coding gene Chr10:46693929-46741052 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017633
protein coding gene Chr10:42154423-42200490 (+)
PWK/PhJ MGP_PWKPhJ_G0016316
protein coding gene Chr10:40858706-40906826 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016101
protein coding gene Chr10:41988118-42035160 (+)
WSB/EiJ MGP_WSBEiJ_G0016600
protein coding gene Chr10:42421763-42470986 (+)



Homology
more
  • Human Ortholog
    RTN4IP1, reticulon 4 interacting protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RTN4IP1, reticulon 4 interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NIMP, OPA10
  • Links
    NCBI Gene ID: 84816
    neXtProt AC: NX_Q8WWV3
    UniProt: Q8WWV3

  • Chr Location
    6q21; chr6:106559237-106630921 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 170728 NCBI Gene Model | MGI Sequence Detail 46151 C57BL/6J ±  kb
transcript NM_130892 RefSeq | MGI Sequence Detail 2982 C57BL/6  
polypeptide Q924D0 UniProt | EBI | MGI Sequence Detail 396 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 33
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1277154
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233622 Angebault C, et al., Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. Am J Hum Genet. 2015 Nov 5;97(5):754-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory