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Akap9
Gene Detail
 Symbol
Name
ID
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
MGI:2178217
Synonyms 5730481H23Rik, AKAP450, G1-448-15, mei2-5, mKIAA0803, repro12
Feature Type protein coding gene
Genetic Map
Chromosome 5
2.26 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr5:3928054-4080209 bp, + strand
From VEGA annotation of GRCm38

  152156 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17517  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Akap9

Human
homologs
Human Homolog AKAP9, A kinase (PRKA) anchor protein 9
NCBI Gene ID 10142
neXtProt AC  NX_Q99996
Human Synonyms  AKAP350, AKAP450, AKAP-9, CG-NAP, HYPERION, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO
Human Chr (Location)  7q21-q22; chr7:91940867-92110673 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AKAP9
Alleles
and
phenotypes
All alleles(23) : Targeted(3) Gene trapped(18) Chemically induced(2)
 
Mice homozygous for a chemically induced allele exhibit male infertily with abnormal spermatogenesis and Sertoli maturation.
 
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process Sertoli cell development, spermatogenesis
Component centrosome, ciliary basal body, ...
Function ion channel binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (42)    Tissues (29)    Images (14)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 42
cDNA source data(16)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000016263 (Evidence)
Ensembl Gene ModelENSMUSG00000040407 (Evidence)
Entrez Gene100986 (Evidence)
DFCITC1574916, TC1597052, TC1599917, TC1606945
NIA Mouse Gene IndexU043845
Consensus CDS ProjectCCDS19070.1
International Mouse Knockout Project StatusAkap9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016263 VEGA Gene Model | MGI Sequence Detail 152156 C57BL/6J ±  kb
transcript OTTMUST00000038992 VEGA | MGI Sequence Detail 12022 Not Applicable 
polypeptide OTTMUSP00000017425 VEGA | MGI Sequence Detail 3779 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(16) UniProt(9)
Polymorphisms SNPs within 2kb(1184 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1186)
Protein-related
information
ResourceIDDescription
InterPro IPR019528 Pericentrin/AKAP-450 centrosomal targeting domain
Protein Ontology PR:000003896 A-kinase anchor protein 9
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:198499 Schimenti KJ, et al., AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice. Genetics. 2013 Jun;194(2):447-57
All references(48)
Other
accession IDs
MGI:1913889, MGI:2141218, MGI:2141306, MGI:3050556, MGI:3512794

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory