About   Help   FAQ
Tmem259
Gene Detail
Symbol

Name
ID
Tmem259
transmembrane protein 259
MGI:2177957
Synonyms
membralin, ORF61
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:79974948-79984330 bp, - strand
From VEGA annotation of GRCm38

  9383 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14122  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TMEM259
Gene Tree: Tmem259

Human
homologs
TMEM259, transmembrane protein 259
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 91304
neXtProt AC: NX_Q4ZIN3

Human Synonyms: ASBABP1, C19orf6, MBRL, MEMBRALIN, R32184_3

Human Chr (Location): 19p13.3; chr19:1009651-1021169 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(3) Transgenic(1)
Genomic Mutations involving Tmem259 (1)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.
 
Interactions
Tmem259 interacts with 47 markers (Mir29b-1, Mir29b-2, Mir29c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(100)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase tmem259 ; ZFIN tmem259    NEW 
Molecular
reagents
All nucleic(102) Genomic(1) cDNA(100) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000019134 (Evidence)
Ensembl Gene Model ENSMUSG00000013858 (Evidence)
Entrez Gene 216157 (Evidence)
UniGene 29442
DFCI TC1581488, TC1598361, TC1600050, TC1604636
NIA Mouse Gene Index U031998
Consensus CDS Project CCDS24002.1
International Mouse Phenotyping Consortium Status Tmem259
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019134 VEGA Gene Model | MGI Sequence Detail 9383 C57BL/6J ±  kb
transcript OTTMUST00000045865 VEGA | MGI Sequence Detail 2225 Not Applicable 
polypeptide OTTMUSP00000020663 VEGA | MGI Sequence Detail 574 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019144 Membralin
Protein Ontology PR:000012036 membralin
References
(Earliest) J:80938 Andersson O, et al., Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system. Brain Res Gene Expr Patterns. 2002 Oct;1(3-4):205-12
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)
Other
accession IDs
MGI:2158302

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory