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Vasn
Gene Detail
 Symbol
Name
ID
Vasn
vasorin
MGI:2177651
Synonyms 2610528G05Rik, ATIA, Slitl2
Feature Type protein coding gene
Genetic Map
Chromosome 16
2.46 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:4639941-4650802 bp, + strand
From VEGA annotation of GRCm38

  10862 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36929  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 3 zebrafish

Gene Tree: Vasn

Human
homologs
Human Homolog VASN, vasorin
NCBI Gene ID 114990
neXtProt AC  NX_Q6EMK4
Human Synonyms  SLITL2
Human Chr (Location)  16p13.3; chr16:4371848-4383528 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from APF )
 
Mice homozygous for a targeted allele exhibit increased sensitivity to TNFalpha-induced lethality, TNFalpha-, cycloheximide-, or CoCl2-induced cell death, and reduced male fertility.
 
Interactions
Vasn interacts with 100 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cellular response to hypoxia, cellular response to redox state, ...
Component cell surface, extracellular space, ...
Function protein binding, transforming growth factor beta binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (156)    Tissues (91)    Images (64)
Theiler Stages: 13, 15, 17, 19, 20, 21, 22, 23, 25
Assay TypeResults
RNA in situ 69
In situ reporter (knock in) 87
cDNA source data(67)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(67) cDNA(67)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024383 (Evidence)
Ensembl Gene ModelENSMUSG00000039646 (Evidence)
Entrez Gene246154 (Evidence)
UniGene482140
DFCITC1574835, TC1654196
DoTSDT.101400818, DT.101400821, DT.488226
NIA Mouse Gene IndexU016760, U075298
Consensus CDS ProjectCCDS27921.1
International Mouse Knockout Project StatusVasn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024383 VEGA Gene Model | MGI Sequence Detail 10862 C57BL/6J ±  kb
transcript OTTMUST00000060757 VEGA | MGI Sequence Detail 2829 Not Applicable 
polypeptide OTTMUSP00000029771 VEGA | MGI Sequence Detail 673 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000017262 vasorin
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(36)
Other
accession IDs
MGI:1921457

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory