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Vasn Gene Detail
Summary
  • Symbol
    Vasn
  • Name
    vasorin
  • Synonyms
    2610528G05Rik, ATIA, Slitl2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2177651
    NCBI Gene: 246154
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:4639941-4650802 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 2.46 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2177651
protein coding gene Chr16:4639941-4651166 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022468
protein coding gene Chr16:1142613-1153475 (+)
A/J MGP_AJ_G0022430
protein coding gene Chr16:966613-977390 (+)
AKR/J MGP_AKRJ_G0022407
protein coding gene Chr16:1155290-1166151 (+)
BALB/cJ MGP_BALBcJ_G0022435
protein coding gene Chr16:1120210-1131080 (+)
C3H/HeJ MGP_C3HHeJ_G0022202
protein coding gene Chr16:1171902-1182765 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022884
protein coding gene Chr16:1221709-1232583 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020405
protein coding gene Chr16:908385-919175 (+)
CAST/EiJ MGP_CASTEiJ_G0021728
protein coding gene Chr16:1161188-1171969 (+)
CBA/J MGP_CBAJ_G0022171
protein coding gene Chr16:1282408-1293284 (+)
DBA/2J MGP_DBA2J_G0022302
protein coding gene Chr16:1078114-1089042 (+)
FVB/NJ MGP_FVBNJ_G0022277
protein coding gene Chr16:1062799-1073671 (+)
LP/J MGP_LPJ_G0022370
protein coding gene Chr16:1144894-1155952 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022299
protein coding gene Chr16:1154803-1165671 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022896
protein coding gene Chr16:1119258-1130132 (+)
PWK/PhJ MGP_PWKPhJ_G0021468
protein coding gene Chr16:1138340-1149710 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021299
protein coding gene Chr16:1208399-1221301 (+)
WSB/EiJ MGP_WSBEiJ_G0021777
protein coding gene Chr16:1132245-1143138 (+)



Homology
more
  • Human Ortholog
    VASN, vasorin
  • Vertebrate Orthologs
    11
  • Human Ortholog
    VASN, vasorin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SLITL2
  • Links
    NCBI Gene ID: 114990
    neXtProt AC: NX_Q6EMK4
    UniProt: Q6EMK4

  • Chr Location
    16p13.3; chr16:4371848-4383528 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted allele exhibit increased sensitivity to TNFalpha-induced lethality, TNFalpha-, cycloheximide-, or CoCl2-induced cell death, and reduced male fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039646 Ensembl Gene Model | MGI Sequence Detail 10862 C57BL/6J ±  kb
    transcript ENSMUST00000038770 Ensembl | MGI Sequence Detail 2829 Not Applicable  
    polypeptide ENSMUSP00000045162 Ensembl | MGI Sequence Detail 673 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 69
      cDNA 68
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1921457
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:271365 Rimon-Dahari N, et al., Vasorin: a newly identified regulator of ovarian folliculogenesis. FASEB J. 2018 Apr;32(4):2124-2136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    02/23/2021
    MGI 6.16
    The Jackson Laboratory