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Scrt1 Gene Detail
Summary
  • Symbol
    Scrt1
  • Name
    scratch family zinc finger 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2176606
    NCBI Gene: 170729
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76516203-76522129 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.01 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2176606
protein coding gene Chr15:76516203-76522499 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021996
protein coding gene Chr15:76594198-76600124 (-)
A/J MGP_AJ_G0021954
protein coding gene Chr15:73805597-73811564 (-)
AKR/J MGP_AKRJ_G0021937
protein coding gene Chr15:75806680-75812606 (-)
BALB/cJ MGP_BALBcJ_G0021963
protein coding gene Chr15:73833780-73839681 (-)
C3H/HeJ MGP_C3HHeJ_G0021735
protein coding gene Chr15:75854621-75860382 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022403
protein coding gene Chr15:79458284-79465791 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019932
protein coding gene Chr15:70469230-70475168 (-)
CAST/EiJ MGP_CASTEiJ_G0021254
protein coding gene Chr15:76656430-76662348 (-)
CBA/J MGP_CBAJ_G0021702
protein coding gene Chr15:81968751-81974734 (-)
DBA/2J MGP_DBA2J_G0021827
protein coding gene Chr15:73342251-73348204 (-)
FVB/NJ MGP_FVBNJ_G0021807
protein coding gene Chr15:72398627-72404570 (-)
LP/J MGP_LPJ_G0021898
protein coding gene Chr15:76692809-76699884 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021832
protein coding gene Chr15:87299383-87306713 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022423
protein coding gene Chr15:76059871-76066861 (-)
PWK/PhJ MGP_PWKPhJ_G0020995
protein coding gene Chr15:73508130-73514055 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020835
protein coding gene Chr15:75777449-75783352 (-)
WSB/EiJ MGP_WSBEiJ_G0021306
protein coding gene Chr15:76164566-76170492 (-)



Homology
more
  • Human Ortholog
    SCRT1, scratch family transcriptional repressor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCRT1, scratch family transcriptional repressor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SCRT, ZNF898
  • Links
    NCBI Gene ID: 83482
    neXtProt AC: NX_Q9BWW7
    UniProt: Q9BWW7

  • Chr Location
    8q24.3; chr8:144330565-144336281 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Scrt1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 170729 NCBI Gene Model | MGI Sequence Detail 5927 C57BL/6J ±  kb
transcript NM_130893 RefSeq | MGI Sequence Detail 4010 C57BL/6  
polypeptide Q99M85 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 2
    cDNA 24
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 54
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 6
    Phenotypes 24
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:239534 Monaghan CE, et al., REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E406-E415

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory