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Scrt1 Gene Detail
Summary
  • Symbol
    Scrt1
  • Name
    scratch family zinc finger 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2176606
    NCBI Gene: 170729
Location & Maps
more
  • Sequence Map
    Chr15:76516203-76522129 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5927 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.01 cM, cytoband E1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SCRT1, scratch family transcriptional repressor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCRT1, scratch family transcriptional repressor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SCRT, ZNF898
  • Links
    NCBI Gene ID: 83482
    neXtProt AC: NX_Q9BWW7

  • Chr Location
    8q24.3; chr8:144330565-144336281 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Scrt1
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 170729 NCBI Gene Model | MGI Sequence Detail 5927 C57BL/6J ±  kb
transcript NM_130893 RefSeq | MGI Sequence Detail 4010 C57BL/6  
polypeptide Q99M85 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 1
    cDNA 23
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 4
    Phenotypes 24
  • Earliest
    J:74951 Nakakura EK, et al., Mammalian Scratch: a neural-specific Snail family transcriptional repressor. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4010-5
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory