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Arid5b
Gene Detail
Symbol

Name
ID
Arid5b
AT rich interactive domain 5B (MRF1-like)
MGI:2175912
Synonyms
5430435G07Rik, Desrt, Mrf2, Mrf2alpha, Mrf2beta
Feature Type
protein coding gene
Genetic Map
Chromosome 10
35.14 cM, cytoband B5.1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:68095593-68278726 bp, - strand
From Ensembl annotation of GRCm38

  183134 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45872  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Arid5b

Human
homologs
Human Homolog ARID5B, AT rich interactive domain 5B (MRF1-like)
NCBI Gene ID 84159
neXtProt AC  NX_Q14865
Human Synonyms  DESRT, MRF2, MRF-2
Human Chr (Location)  10q21.2; chr10:61901254-62096948 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(242) : Gene trapped(239) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene experience a high level of mortality perinatally or earlier. Growth rates are low and mice remain small throughout live. There are abnormalities in various organ systems as well as the reproductive system. Fertility is reduced.
 
Interactions
Arid5b interacts with 233 markers (Mir7-1, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process adipose tissue development, adrenal gland development, ...
Component nucleus
Function DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (206)    Tissues (143)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 162
RT-PCR 44
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) Genomic(1) cDNA(13) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000019947 (Evidence)
Entrez Gene71371 (Evidence)
DFCITC1581194, TC1591150, TC1586242, TC1604273, TC1597939
DoTSDT.101257993, DT.94157142, DT.87041221, DT.101734921, DT.40151156, DT.101376070
NIA Mouse Gene IndexU031895
Consensus CDS ProjectCCDS35929.1
International Mouse Knockout Project StatusArid5b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019947 Ensembl Gene Model | MGI Sequence Detail 183134 C57BL/6J ±  kb
transcript ENSMUST00000020106 Ensembl | MGI Sequence Detail 4494 Not Applicable 
polypeptide ENSMUSP00000020106 Ensembl | MGI Sequence Detail 1188 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(12) UniProt(3)
Polymorphisms
SNPs within 2kb(1624 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001606 ARID/BRIGHT DNA-binding domain
Protein Ontology PR:000004270 AT-rich interactive domain-containing protein 5B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:182258 Taher L, et al., Global gene expression analysis of murine limb development. PLoS One. 2011;6(12):e28358
All references(51)
Other
accession IDs
MGI:1918621, MGI:2143624

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory