About   Help   FAQ
Acot3 Gene Detail
Summary
  • Symbol
    Acot3
  • Name
    acyl-CoA thioesterase 3
  • Synonyms
    Pte2a, PTE-Ia
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159619
    NCBI Gene: 171281
Location & Maps
more
  • Sequence Map
    Chr12:84052144-84059565 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7422 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 39.02 cM, cytoband D3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ACOT1, acyl-CoA thioesterase 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ACOT1, acyl-CoA thioesterase 1
    Orthology source: HomoloGene
  • Synonyms
    ACH2, CTE-1, LACH2
  • Links
    NCBI Gene ID: 641371
    neXtProt AC: NX_Q86TX2

  • Chr Location
    chr14:73493234-73543799 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    1
  • Chemically induced (other)
    1
  • Genomic Mutations
    1 involving Acot3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027601 VEGA Gene Model | MGI Sequence Detail 7422 C57BL/6J ±  kb
transcript OTTMUST00000068318 VEGA | MGI Sequence Detail 2594 Not Applicable  
polypeptide OTTMUSP00000034516 VEGA | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    52 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145005
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:59046 Hunt MC, et al., Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism. J Biol Chem. 1999 Nov 26;274(48):34317-26
  • Latest
    J:112727 Hunt MC, et al., Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. FASEB J. 2006 Sep;20(11):1855-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/22/2016
MGI 6.06
The Jackson Laboratory