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Arr3 Gene Detail
Summary
  • Symbol
    Arr3
  • Name
    arrestin 3, retinal
  • Synonyms
    Arr4, arrestin 4, CAR, cone arrestin, mCAR, mCARFL, X-arrestin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159617
    NCBI Gene: 170735
  • Gene Overview
    MyGene.info: ARR3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:100605497-100618493 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 43.72 cM, cytoband C2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2159617
protein coding gene ChrX:100605480-100618953 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035945
protein coding gene ChrX:97064988-97077992 (+)
A/J MGP_AJ_G0035930
protein coding gene ChrX:97108658-97121636 (+)
AKR/J MGP_AKRJ_G0035846
protein coding gene ChrX:99891792-99906938 (+)
BALB/cJ MGP_BALBcJ_G0035913
protein coding gene ChrX:95852862-95865846 (+)
C3H/HeJ MGP_C3HHeJ_G0035622
protein coding gene ChrX:97496889-97509863 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036442
protein coding gene ChrX:99977437-99990410 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033272
protein coding gene ChrX:94883145-94896033 (+)
CAST/EiJ MGP_CASTEiJ_G0034909
protein coding gene ChrX:81799788-81812842 (+)
CBA/J MGP_CBAJ_G0035597
protein coding gene ChrX:103071902-103084889 (+)
DBA/2J MGP_DBA2J_G0035751
protein coding gene ChrX:96314501-96327479 (+)
FVB/NJ MGP_FVBNJ_G0035689
protein coding gene ChrX:95713718-95726889 (+)
LP/J MGP_LPJ_G0035841
protein coding gene ChrX:98038274-98059974 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035724
protein coding gene ChrX:107602458-107615566 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036469
protein coding gene ChrX:96781131-96794762 (+)
PWK/PhJ MGP_PWKPhJ_G0034608
protein coding gene ChrX:79419962-79433271 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034436
protein coding gene ChrX:82684096-82700270 (+)
WSB/EiJ MGP_WSBEiJ_G0035048
protein coding gene ChrX:95498590-95511585 (+)



Homology
more
  • Human Ortholog
    ARR3, arrestin 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARR3, arrestin 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARRX, cArr, MYP26
  • Links
    NCBI Gene ID: 407
    neXtProt AC: NX_P36575
    UniProt: P36575

  • Chr Location
    Xq13.1; chrX:70268335-70281840 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Mice homozygous for a null allele exhibit normal cone electrophysiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060890 Ensembl Gene Model | MGI Sequence Detail 12997 C57BL/6J ±  kb
transcript ENSMUST00000113769 Ensembl | MGI Sequence Detail 1359 Not Applicable  
polypeptide ENSMUSP00000109398 Ensembl | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 14
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 66
    Developmental Gene Expression 31
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:61371 Hong DH, et al., A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3). Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3649-54
  • Latest
    J:263267 Serjanov D, et al., Laminin beta2 Chain Regulates Retinal Progenitor Cell Mitotic Spindle Orientation via Dystroglycan. J Neurosci. 2018 Jun 27;38(26):5996-6010

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory