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Arr3 Gene Detail
Summary
  • Symbol
    Arr3
  • Name
    arrestin 3, retinal
  • Synonyms
    Arr4, arrestin 4, CAR, cone arrestin, mCAR, mCARFL, X-arrestin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159617
    NCBI Gene: 170735
  • Gene Overview
    MyGene.info: ARR3
Location & Maps
more
  • Sequence Map
    ChrX:100605497-100618493 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12997 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ARR3, arrestin 3 retinal (X-arrestin)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARR3, arrestin 3 retinal (X-arrestin)
    Orthology source: HomoloGene
  • Synonyms
    ARRX
  • Links
    NCBI Gene ID: 407
    neXtProt AC: NX_P36575

  • Chr Location
    Xcen-q21; chrX:70263503-70281840 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    7 phenotype references
  • All Mutations and Alleles
    5
  • Endonuclease-mediated
    1
  • Targeted
    4
Mice homozygous for a null allele exhibit normal cone electrophysiology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018283 VEGA Gene Model | MGI Sequence Detail 12997 C57BL/6J ±  kb
transcript OTTMUST00000044179 VEGA | MGI Sequence Detail 1359 Not Applicable  
polypeptide OTTMUSP00000019862 VEGA | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    104 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 57
    Developmental Gene Expression 23
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:61371 Hong DH, et al., A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3). Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3649-54
  • Latest
    J:230942 Deming JD, et al., Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5407-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory