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Arr3
Gene Detail
Symbol

Name
ID
Arr3
arrestin 3, retinal
MGI:2159617
Synonyms
Arr4, arrestin 4, CAR, cone arrestin, mCAR, mCARFL, X-arrestin
Feature Type
protein coding gene
Genetic Map
Chromosome X
43.72 cM, cytoband C2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:100605497-100618493 bp, + strand
From VEGA annotation of GRCm38

  12997 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3182  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: arrestin
Gene Tree: Arr3

Human
homologs
Human Homolog ARR3, arrestin 3, retinal (X-arrestin)
NCBI Gene ID 407
neXtProt AC  NX_P36575
Human Synonyms  ARRX
Human Chr (Location)  Xcen-q21; chrX:70268335-70281993 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
 
Mice homozygous for a null allele exhibit normal cone electrophysiology.
 
Interactions
Arr3 interacts with 82 markers (Mir17, Mir20b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process endocytosis, regulation of protein phosphorylation, ...
Component photoreceptor inner segment, photoreceptor outer segment, ...
Function opsin binding, phosphoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (21 records)
Data Summary: Results (4)    Tissues (2)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
RT-PCR 2
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000018283 (Evidence)
Ensembl Gene ModelENSMUSG00000060890 (Evidence)
Entrez Gene170735 (Evidence)
UniGene95518
DFCITC1589427, TC1592099
DoTSDT.97407482, DT.91337931
NIA Mouse Gene IndexU020056
Consensus CDS ProjectCCDS41075.1
International Mouse Knockout Project StatusArr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018283 VEGA Gene Model | MGI Sequence Detail 12997 C57BL/6J ±  kb
transcript OTTMUST00000044179 VEGA | MGI Sequence Detail 1359 Not Applicable 
polypeptide OTTMUSP00000019862 VEGA | MGI Sequence Detail 381 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(31) UniProt(5)
Polymorphisms
SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000698 Arrestin
InterPro IPR017864 Arrestin, conserved site
InterPro IPR014752 Arrestin, C-terminal
InterPro IPR011022 Arrestin C-terminal-like domain
InterPro IPR011021 Arrestin-like, N-terminal
InterPro IPR014753 Arrestin, N-terminal
InterPro IPR014756 Immunoglobulin E-set
Protein Ontology PR:000004318 arrestin-C
References
(Earliest) J:77794 Zhu X, et al., Mouse cone arrestin gene characterization: promoter targets expression to cone photoreceptors. FEBS Lett. 2002 Jul 31;524(1-3):116-22
(Latest) J:210433 Mandal NA, et al., Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene. Exp Eye Res. 2013 Jan;106:24-33
All references(57)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory