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Syt12 Gene Detail
Summary
  • Symbol
    Syt12
  • Name
    synaptotagmin XII
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159601
    NCBI Gene: 171180
Location & Maps
more
  • Sequence Map
    Chr19:4445908-4477447 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31540 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.07 cM, cytoband A
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SYT12, synaptotagmin 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYT12, synaptotagmin 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SYT11, sytXII
  • Links
    NCBI Gene ID: 91683
    neXtProt AC: NX_Q8IV01

  • Chr Location
    11q13.2; chr11:67006773-67050863 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    1
  • Targeted
    4
  • Incidental Mutations
    APF
Mice homozygous for a knock-in allele are viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028326 VEGA Gene Model | MGI Sequence Detail 31540 C57BL/6J ±  kb
transcript OTTMUST00000070208 VEGA | MGI Sequence Detail 3581 Not Applicable  
polypeptide OTTMUSP00000035748 VEGA | MGI Sequence Detail 421 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    112 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:198642 Kaeser-Woo YJ, et al., Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. J Neurosci. 2013 Jun 5;33(23):9769-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory