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Arhgap4
Gene Detail
Symbol

Name
ID
Arhgap4
Rho GTPase activating protein 4
MGI:2159577
Synonyms
A130009C12Rik, A530015A20Rik, c1, Rgc1
Feature Type
protein coding gene
Genetic Map
Chromosome X
37.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:73891442-73921870 bp, - strand
From VEGA annotation of GRCm38

  30429 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: ARHGAP4
Gene Tree: Arhgap4

Human
homologs
ARHGAP4, Rho GTPase activating protein 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 393
neXtProt AC: NX_P98171

Human Synonyms: C1, p115, RGC1, RhoGAP4, SrGAP4

Human Chr (Location): Xq28; chrX:153907376-153926260 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Arhgap4 interacts with 298 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process negative regulation of axon extension, negative regulation of cell migration, ...
Component cytoplasm, focal adhesion, ...
Function GTPase activator activity, Rac GTPase binding
External Resources: FuncBase
Expression
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase arhgap4    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000017679 (Evidence)
Ensembl Gene Model ENSMUSG00000031389 (Evidence)
Entrez Gene 171207 (Evidence)
DFCI TC1626813, TC1643424, TC1583559, TC1699204, TC1644272
Consensus CDS Project CCDS41014.1, CCDS53100.1, CCDS53101.1
International Mouse Phenotyping Consortium Status Arhgap4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017679 VEGA Gene Model | MGI Sequence Detail 30429 C57BL/6J ±  kb
transcript OTTMUST00000055037 VEGA | MGI Sequence Detail 6299 Not Applicable 
polypeptide OTTMUSP00000026297 VEGA | MGI Sequence Detail 965 Not Applicable 

For the selected sequences
All sequences(133) RefSeq(25) UniProt(16)
Polymorphisms
SNPs within 2kb(113 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001060 FCH domain
InterPro IPR000198 Rho GTPase-activating protein domain
InterPro IPR008936 Rho GTPase activation protein
InterPro IPR001452 Src homology-3 domain
InterPro IPR011511 Variant SH3
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:182891 Chen XW, et al., A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. Mol Biol Cell. 2011 Jan 1;22(1):141-52
All references(24)
Other
accession IDs
MGI:2441775, MGI:2441804

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory