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Arhgap4 Gene Detail
Summary
  • Symbol
    Arhgap4
  • Name
    Rho GTPase activating protein 4
  • Synonyms
    A130009C12Rik, A530015A20Rik, c1, Rgc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159577
    NCBI Gene: 171207
  • Gene Overview
    MyGene.info: ARHGAP4
Location & Maps
more
  • Sequence Map
    ChrX:73891442-73921870 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30429 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.45 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARHGAP4, Rho GTPase activating protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARHGAP4, Rho GTPase activating protein 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1, p115, RGC1, RhoGAP4, SrGAP4
  • Links
    NCBI Gene ID: 393
    neXtProt AC: NX_P98171

  • Chr Location
    Xq28; chrX:153907376-153926260 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017679 VEGA Gene Model | MGI Sequence Detail 30429 C57BL/6J ±  kb
transcript OTTMUST00000055037 VEGA | MGI Sequence Detail 6299 Not Applicable  
polypeptide OTTMUSP00000026297 VEGA | MGI Sequence Detail 965 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    113 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2441775, MGI:2441804
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:182891 Chen XW, et al., A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. Mol Biol Cell. 2011 Jan 1;22(1):141-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory