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Arhgap4 Gene Detail
Summary
  • Symbol
    Arhgap4
  • Name
    Rho GTPase activating protein 4
  • Synonyms
    A130009C12Rik, A530015A20Rik, c1, Rgc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159577
    NCBI Gene: 171207
  • Gene Overview
    MyGene.info: ARHGAP4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:73894352-73911346 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2159577
protein coding gene ChrX:73891442-73921870 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035824
protein coding gene ChrX:69669213-69704039 (-)
A/J MGP_AJ_G0035805
protein coding gene ChrX:69867792-69899560 (-)
AKR/J MGP_AKRJ_G0035730
protein coding gene ChrX:71710269-71743238 (-)
BALB/cJ MGP_BALBcJ_G0035790
protein coding gene ChrX:68895465-68925836 (-)
C3H/HeJ MGP_C3HHeJ_G0035495
protein coding gene ChrX:70147387-70179757 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036320
protein coding gene ChrX:71815879-71847150 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033164
protein coding gene ChrX:68899379-68929491 (-)
CAST/EiJ MGP_CASTEiJ_G0034786
protein coding gene ChrX:55498954-55530251 (-)
CBA/J MGP_CBAJ_G0035470
protein coding gene ChrX:73810339-73843223 (-)
DBA/2J MGP_DBA2J_G0035627
protein coding gene ChrX:69323941-69354521 (-)
FVB/NJ MGP_FVBNJ_G0035571
protein coding gene ChrX:68657967-68690322 (-)
LP/J MGP_LPJ_G0035712
protein coding gene ChrX:70454027-70485054 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035609
protein coding gene ChrX:76363573-76395222 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036342
protein coding gene ChrX:69494951-69526187 (-)
PWK/PhJ MGP_PWKPhJ_G0034485
protein coding gene ChrX:53506164-53537352 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034319
protein coding gene ChrX:56395725-56426047 (-)
WSB/EiJ MGP_WSBEiJ_G0034927
protein coding gene ChrX:68766228-68797732 (-)



Homology
more
  • Human Ortholog
    ARHGAP4, Rho GTPase activating protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARHGAP4, Rho GTPase activating protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1, p115, RGC1, RhoGAP4, SrGAP4
  • Links
    NCBI Gene ID: 393
    neXtProt AC: NX_P98171
    UniProt: P98171

  • Chr Location
    Xq28; chrX:153907376-153926260 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 171207 NCBI Gene Model | MGI Sequence Detail 16995 C57BL/6J ±  kb
transcript NM_138630 RefSeq | MGI Sequence Detail 3321 C57BL/6  
polypeptide NP_619536 RefSeq | MGI Sequence Detail 955 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:2441775, MGI:2441804
References
more
  • Summaries
    All 23
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory