About   Help   FAQ
Tmie
Gene Detail
 Symbol
Name
ID
Tmie
transmembrane inner ear
MGI:2159400
Synonyms 5131400L21Rik, Mm.87012
Feature Type protein coding gene
Genetic Map
Chromosome 9
60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr9:110865711-110880113 bp, - strand
From VEGA annotation of GRCm38

  14403 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17155  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tmie

Human
homologs
Human Homolog TMIE, transmembrane inner ear
NCBI Gene ID 259236
neXtProt AC  NX_Q8NEW7
Human Synonyms  DFNB6
Human Chr (Location)  3p21; chr3:46693851-46710923 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TMIE
Alleles
and
phenotypes
All alleles(7) : Targeted(2) Gene trapped(2) Spontaneous(3)
 
Mutations in this gene cause circling behavior and deafness in homozygous mice.
 
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process inner ear morphogenesis, sensory perception of sound
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021713 (Evidence)
Ensembl Gene ModelENSMUSG00000049555 (Evidence)
Entrez Gene20776 (Evidence)
UniGene390229
NIA Mouse Gene IndexU031373
Consensus CDS ProjectCCDS23578.1
International Mouse Knockout Project StatusTmie
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021713 VEGA Gene Model | MGI Sequence Detail 14403 C57BL/6J ±  kb
transcript OTTMUST00000051525 VEGA | MGI Sequence Detail 2802 Not Applicable 
polypeptide OTTMUSP00000024269 VEGA | MGI Sequence Detail 153 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(18) UniProt(3)
Polymorphisms SNPs within 2kb(143 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000016442 transmembrane inner ear expressed protein
References (Earliest) J:13132 DEOL MS, et al., The spinner mouse. J Hered. 1962 May-Jun;53:133-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGD-MRK-14553, MGI:2443547, MGI:98395

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory