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Idh3b
Gene Detail
 Symbol
Name
ID
Idh3b
isocitrate dehydrogenase 3 (NAD+) beta
MGI:2158650
Feature Type protein coding gene
Genetic Map
Chromosome 2
63.20 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:130279309-130284547 bp, - strand
From VEGA annotation of GRCm38

  5239 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5035  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: 3-isopropylmalate dehydrogenase
Gene Tree: Idh3b

Human
homologs
Human Homolog IDH3B, isocitrate dehydrogenase 3 (NAD+) beta
NCBI Gene ID 3420
neXtProt AC  NX_O43837
Human Synonyms  H-IDHB, RP46
Human Chr (Location)  20p13; chr20:2658395-2664219 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human IDH3B
Alleles
and
phenotypes
All alleles(3) : Targeted(1) Gene trapped(2)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process 2-oxoglutarate metabolic process, isocitrate metabolic process, ...
Component mitochondrion
Function isocitrate dehydrogenase (NAD+) activity, oxidoreductase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (118)    Tissues (97)    Images (20)
Theiler Stages: 22
Assay TypeResults
RNA in situ 118
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000015521 (Evidence)
Ensembl Gene ModelENSMUSG00000027406 (Evidence)
Entrez Gene170718 (Evidence)
DFCITC1572606, TC1606847, TC1667790, TC1774341
DoTSDT.55138816, DT.91329254, DT.91441076, DT.94145181, DT.94186183, DT.94241581, DT.99872247
NIA Mouse Gene IndexU023353
Consensus CDS ProjectCCDS16738.1
International Mouse Knockout Project StatusIdh3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015521 VEGA Gene Model | MGI Sequence Detail 5239 C57BL/6J ±  kb
transcript OTTMUST00000036851 VEGA | MGI Sequence Detail 1616 Not Applicable 
polypeptide OTTMUSP00000016536 VEGA | MGI Sequence Detail 384 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001804 Isocitrate and isopropylmalate dehydrogenases family
InterPro IPR004434 Isocitrate dehydrogenase NAD-dependent
InterPro IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
InterPro IPR024084 Isopropylmalate dehydrogenase-like domain
Protein Ontology PR:000008890 isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:2139470

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory